Results 291 to 300 of about 31,210 (332)

Phosphatidylserine decarboxylase

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997
Phosphatidylserine decarboxylase (PSD) is an important enzyme in the synthesis of phosphatidylethanolamine in both prokaryotes and eukaryotes. The cloned bacterial gene encodes an integral membrane protein that is first made as a proenzyme, and subsequently proteolyzed to an alpha subunit, containing a pyruvoyl prosthetic group, and a beta subunit. Two
openaire   +2 more sources

Optimized synthesis of phosphatidylserine

Amino Acids, 2010
The synthesis of phosphatidyl serine containing saturated fatty acids was thoroughly studied and optimized in order to establish a protocol amenable to large-scale synthesis. The key step was a one-pot multicomponent reaction involving an O-benzyl phosphorodiamidite, protected serine and diacylglycerol, followed by in situ oxidation of the resulting ...
GUANTI, GIUSEPPE, BANFI, LUCA, BASSO, ANDREA, BONDANZA L, GUGLIERI G, POWLES K, RIVA, RENATA   +6 more
openaire   +2 more sources

Metabolism and functions of phosphatidylserine

Progress in Lipid Research, 2005
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss the available information on the regulation of PS biosynthesis in these organisms ...
Jean E, Vance, Rineke, Steenbergen
openaire   +2 more sources

Changes in the phospholipid molecular species in water-boiled salted duck during processing based on shotgun lipidomics.

Food Research International, 2020
Knowledge of the changes in the phospholipid molecular species during processing is helpful to understanding the complicated mechanisms of lipid degradation and transformation. The shotgun lipidomics strategy was utilized to analyze the phospholipid (PL)
Cong Li, Xinfu Li, Qianli Huang, You Zhuo, Baocai Xu, Zhouping Wang   +5 more
semanticscholar   +1 more source

Phosphatidylserine-mediated oral tolerance

Cellular Immunology, 2023
Phosphatidylserine (PS) is an anionic phospholipid exposed on the surface of apoptotic cells. The exposure of PS typically recruits and signals phagocytes to engulf and silently clear these dying cells to maintain tolerance via immunological ignorance.
Nhan H, Nguyen, Vincent, Chak, Katherine, Keller, Helen, Wu, Sathy V, Balu-Iyer   +4 more
openaire   +2 more sources

Phosphatidylserine for the Athlete

Strength & Conditioning Journal, 2015
POSITIVE ADAPTATIONS FROM TRAINING ONLY OCCUR WHEN RESTORATION EXCEEDS THE CATABOLIC DOSAGE RECEIVED DURING TRAINING. NUMEROUS FACTORS AFFECT RECOVERY, SUCH AS ADDITIONAL LIFE STRESS. THE CUMULATIVE STRESS CAN NEGATIVELY AFFECT RESTORATION, AS WELL AS PERFORMANCE.
Jeremy Carter, Mike Greenwood
openaire   +1 more source

Inhibition of VSV binding and infectivity by phosphatidylserine: Is phosphatidylserine a VSV-binding site?

Cell, 1983
Recently we described a saturable, high-affinity binding site for vesicular stomatitis virus (VSV) on the surface of Vero cells that appears to mediate viral infectivity. To isolate this binding site, we have extracted Vero cells with the detergent, octyl-beta-D-glucopyranoside.
R, Schlegel, T S, Tralka, M C, Willingham, I, Pastan   +3 more
openaire   +2 more sources

Study on the in situ aggregation of liposomes with negatively charged phospholipids for use as injectable depot formulation.

Colloids and Surfaces B: Biointerfaces, 2018
Compared to conventional parenteral formulations injectable depot formulations, owing to a sustained drug release, offer several advantages, such as a reduced dosing frequency - and consequent improved compliance - or a predictable release profile ...
Lisa Rahnfeld, J. Thamm, F. Steiniger, P. van Hoogevest, Paola Luciani   +4 more
semanticscholar   +1 more source

A REVIEW OF PHOSPHATIDYLSERINE PHARMACOLOGICAL AND CLINICAL EFFECTS. IS PHOSPHATIDYLSERINE A DRUG FOR THE AGEING BRAIN?

Pharmacological Research, 1996
INTRODUCTION the first compound have been demonstrated on theCNS [7], and of the second on immune responses [8].The history of phosphatidylserine (PtdSer) beganmore than 50 years ago with its identification byFolch [1], as a constituent of the cephaline fraction, up BIOCHEMICAL ACTIONSto its clinical use for the treatment of the ‘ageingbrain’ [2]. This
G, Pepeu, I M, Pepeu, L, Amaducci
openaire   +2 more sources

Integrated Lipidomics and Transcriptomics Characterization upon Aging-Related Changes of Lipid Species and Pathways in Human Bone Marrow Mesenchymal Stem Cells.

Journal of Proteome Research, 2019
Aberrant differentiations of bone mesenchymal stem cells (BMSCs) have proved to be associated with the occurrence of senile osteoporosis. However, mechanisms of this phenomenon relative to abnormal lipid metabolism remain unclear.
Xin Lu, Yue Chen, Huiyu Wang, Yunfan Bai, Jianxiang Zhao, Xiaohan Zhang, Li Liang, Yang Chen, Chenfei Ye, Yiqun Li, Yi Zhang, Y. Li, Ting Ma   +12 more
semanticscholar   +1 more source