Results 211 to 220 of about 31,996 (262)

Translating Mechanistic Insights Into Action and Revealing New Pathways: Machine Learning Approaches in Heart Failure With Preserved Ejection Fraction. [PDF]

J Am Heart Assoc
Imran TF, Kadivar N, Gillotti J, Khalid M, Walsh E, Mendiola E, Avazmohammadi R, Atalay M, Nebipasagil A, Ahmed F, Nguyen C, Wu WC, Karniadakis G, Choudhary G.   +13 more
europepmc   +1 more source

Creatine uptake promotes dendritic cell activation and enhances antitumor immunity. [PDF]

iScience
Kang E, Elsten-Brown J, Wang YC, Lam A, Sanchez E, Wen R, Wang T, Chiang J, Scarborough Q, Li YR, Zhu Y, Huang J, Williams M, Eckl S, Li B, Yang L.   +15 more
europepmc   +1 more source

Evaluating the Safety of Creatine Monohydrate in Adolescents: A Systematic Review of Renal, Hepatic, and Cardiometabolic Outcomes. [PDF]

Cureus
Rubinchuk A, Dulkoski Z, Persaud NA, Wallen M.   +3 more
europepmc   +1 more source

Reducing the Risk of Unintentional Doping From Supplements: A Practical Guide for Athletes and Support Teams. [PDF]

Transl Sports Med
Mancin L, Close GL, Jeukendrup A, Freschi M, Pugh J, Sala M, Baioccato V, Vecchiato M, D'Antona G, Palermi S.   +9 more
europepmc   +1 more source

A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs

Medicinal Chemistry, 2018
Adenosine triphosphate (ATP) is the energy currency of the body; it takes part in various and indispensable metabolic processes for the maintenance of cell homeostasis, degrading to its hydrolysis product, adenosine diphosphate (ADP). Efficient ways to restore ATP are therefore necessary in the cells.
Arkel, Maria, Garbati, Patrizia, Salis, Annalisa, Damonte, Gianluca, Liessi, Nara, Adriano, Enrico, Benatti, Umberto, Balestrino, Maurizio, Millo, Enrico   +8 more
openaire   +4 more sources

A model for phosphocreatine resynthesis

Journal of Applied Physiology, 1997
Nevill, Alan M., David A. Jones, David McIntyre, Gregory C. Bogdanis, and Mary E. Nevill. A model for phosphocreatine resynthesis. J. Appl. Physiol. 82(1): 329–335, 1997.—A model for phosphocreatine (PCr) resynthesis is proposed based on a simple electric circuit, where the PCr store in muscle is likened to the stored charge on the capacitor.
A M, Nevill, D A, Jones, D, McIntyre, G C, Bogdanis, M E, Nevill   +4 more
openaire   +3 more sources

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On the mechanisms of neuroprotection by creatine and phosphocreatine

Journal of Neurochemistry, 2001
Creatine and phosphocreatine were evaluated for their ability to prevent death of cultured striatal and hippocampal neurons exposed to either glutamate or 3‐nitropropionic acid (3NP) and to inhibit the mitochondrial permeability transition in CNS mitochondria. Phosphocreatine (PCr), and to a lesser extent creatine (Cr), but not (5R,10S)‐(+)‐5‐methyl‐10,
Janet Dubinsky, Nickolay Brustovetsky, J M Dubinsky   +2 more
exaly   +3 more sources

A simple analysis of the "phosphocreatine shuttle"

American Journal of Physiology-Cell Physiology, 1984
The diffusive mobility of solutes chemically connected by reversible reactions in cells is analyzed as a problem of facilitated diffusion. By this term we mean that the diffusive flux of any substance, X, which is in one metabolic pathway, is effectively increased when it participates in a second and equilibrium reaction with another substance Y ...
R A, Meyer, H L, Sweeney, M J, Kushmerick   +2 more
openaire   +3 more sources

Determination of creatine and phosphocreatine in muscle biopsy samples by capillary electrophoresis with contactless conductivity detection

Analytica Chimica Acta, 2012
A capillary electrophoresis method with contactless conductivity detection was evaluated as a new approach for quantification of creatine and phosphocreatine in human quadriceps femoris biopsy samples. The running buffers employed consisted of 1 M acetic
Stephan Krähenbühl, Peter Hauser, Hong Heng See   +2 more
exaly   +2 more sources

PHOSPHOCREATINE COMPLEXES

, 2007
The invention relates to novel phosphocreatine complexes useful for the treatment of diseases of the central nervous system, having the following general formula (I): wherein M is a metal, preferably Mg, and An- is an organic or inorganic anion.
BUROV SERGEY VLADIMIROVICH, LENSMAN MICHAEL, POLENOV SERGEY ALEKSANDROVICH, YAKUTSENI PAVEL PAVLOVICH, BALESTRINO MAURIZIO   +4 more
core   +3 more sources