Results 191 to 200 of about 26,828 (231)
Some of the next articles are maybe not open access.
Amelioration of renal ischemic injury by phosphocreatine
Journal of Surgical Research, 1991Phosphocreatine (PCr) is a critical intracellular energy reservoir used in the regeneration of ATP. The aim of this study was to determine the efficacy of exogenously added PCr on preservation of renal function in an in vitro model. The renal artery and ureter of a rat were cannulated and the kidney was subjected to 45 min of normothermic in vivo ...
R, Rodriguez +4 more
openaire +2 more sources
Creatine and Phosphocreatine in the Human Red Cell
British Journal of Haematology, 1968In vitro experiments showed that the concentration of creatine in a mixed population of normal red cells was either unchanged or slightly diminished during incubation at 37° C. for 48 hours in plasma or a buffered medium. If young cells were present there was always a fall in creatine during the early stages of incubation.
openaire +2 more sources
2007
The invention relates to novel phosphocreatine complexes useful for the treatment of diseases of the central nervous system, having the following general formula (I): wherein M is a metal, preferably Mg, and An- is an organic or inorganic anion. The pharmaceutically acceptable salts of such complexes also fall within the scope of the invention.
BALESTRINO, MAURIZIO +4 more
openaire +1 more source
The invention relates to novel phosphocreatine complexes useful for the treatment of diseases of the central nervous system, having the following general formula (I): wherein M is a metal, preferably Mg, and An- is an organic or inorganic anion. The pharmaceutically acceptable salts of such complexes also fall within the scope of the invention.
BALESTRINO, MAURIZIO +4 more
openaire +1 more source
Arzneimittel-Forschung, 1983
Following intravenous administration of 32P-phosphocreatine (50 mg/kg) or an equimolar mixture of creatine + 32P-phosphate (equivalent to 50 mg/kg phosphocreatine) to rats, and examination of an extract of cardiac muscle by HPLC, the proportion of radiolabelled adenosine triphosphate (ATP; up to 3%) was similar in each treatment group at 120 min after ...
W H, Down, L F, Chasseaud, S A, Ballard
openaire +1 more source
Following intravenous administration of 32P-phosphocreatine (50 mg/kg) or an equimolar mixture of creatine + 32P-phosphate (equivalent to 50 mg/kg phosphocreatine) to rats, and examination of an extract of cardiac muscle by HPLC, the proportion of radiolabelled adenosine triphosphate (ATP; up to 3%) was similar in each treatment group at 120 min after ...
W H, Down, L F, Chasseaud, S A, Ballard
openaire +1 more source
Clinical applications of phosphocreatine and related mechanisms
Life SciencesPhosphocreatine (PCr), a naturally occurring creatine phosphorylated molecule, is a high-energy phosphate compound that is one of the most important substances involved in cell energy metabolism, and also has anti-apoptosis and anti-oxidative stress effects.
Jing, Wang +4 more
openaire +2 more sources
The preparation of sodium phosphocreatine
Biochemical Journal, 1948A H, ENNOR, L A, STOCKEN
openaire +3 more sources
Conformational analyses of phosphocreatine and N-methylcreatine, a steric model for phosphocreatine
Journal of the American Chemical Society, 1976George L. Kenyon +3 more
openaire +1 more source
A role for phosphocreatine in adipose inflammation
Nature Reviews Endocrinology, 2022openaire +2 more sources