Results 171 to 180 of about 31,996 (262)

Pitfalls in 2HG Detection With TE‐Optimized MRS at 3T

Journal of Neuroimaging, Volume 36, Issue 5, September/October 2026.
ABSTRACT Background and Purpose In vivo MRS of 2‐hydroxyglutarate (2HG) may provide diagnostic and monitoring biomarkers in isocitrate dehydrogenase (IDH)‐mutated glioma. A previous meta‐analysis has shown good diagnostic accuracy of TE‐optimized PRESS for IDH‐mutated glioma, but most studies feature IDH‐wildtype glioma as a comparison.
Seyma Alcicek, Dunja Simicic, Lindsay Blair, Max Saint‐Germain, Helge J. Zöllner, Christopher W. Davies‐Jenkins, Matthias Holdhoff, John Laterra, Chetan Bettegowda, Karisa C. Schreck, Doris D. Lin, Peter B. Barker, David O. Kamson, Georg Oeltzschner   +13 more
wiley   +1 more source

Beyond plasma signatures: reframing bioenergetic disruption in long COVID as a neurological disorder. [PDF]

J Transl Med
Ostojic SM.
europepmc   +1 more source

Creatine and Phosphocreatine Measurement [PDF]

, 2020
openaire   +1 more source

Efficacy of sodium channel blockers in treating myotonia is independent of action potential sodium current block

The Journal of Physiology, Volume 604, Issue 18, Page 7799-7818, 15 September 2026.
Abstract figure legend Contrary to the prevailing view, the therapeutic efficacy of sodium channel blockers in myotonia does not depend on inhibition of the transient sodium current (NaT) responsible for action potentials. In a mouse model of myotonia congenita, effective concentrations of sodium channel blockers did not reduce NaT, but consistently ...
Phil Walker, Brent Foy, Xueyong Wang, Kaylee M. Pham, Jess Myers, Chris Dupont, Samantha Kohli, Adam S. Deardorff, Andrew A. Voss, Mark M. Rich   +9 more
wiley   +1 more source

Detection of elevated levels of taurine and creatine in the brain of hypoxic-ischemic newborn rat using a magnetic resonance spin echo full intensity acquired localization sequence. [PDF]

Transl Pediatr
Chen J, Shen Z, Li M, Wu M, Wang D, Zhong Z, Chen L, Deng D.   +7 more
europepmc   +1 more source

Combined 31P and 1H MRS show that impaired muscle O2 supply limits ATP synthesis during exercise in systemic sclerosis. [PDF]

Clin Sci (Lond)
Kemp GJ.
europepmc   +1 more source

Sublayer‐ and pathway‐specific control of CA1 input processing by VIP interneurons

The Journal of Physiology, Volume 604, Issue 18, Page 7890-7910, 15 September 2026.
Abstract figure legend Pathway‐ and sublayer‐specific regulation of CA1 pyramidal neurons by VIP interneurons. Left, schematic representation of the principal inhibitory circuit motifs formed by vasoactive intestinal peptide‐expressing interneurons (VIP‐INs) in hippocampal CA1.
Parisa Iloun, Jordan Grenier, Felix Veillette, Lisa Topolnik   +3 more
wiley   +1 more source

Early‐stage myocardial changes are not aggravated by Western diet or ageing in Mybpc3 c.2373insG heterozygous mice

The Journal of Physiology, Volume 604, Issue 18, Page 7594-7639, 15 September 2026.
Abstract figure legend Schematic overview of the results. The disease‐modifying effects were investigated by subjecting wild‐type (WT) and heterozygous (HET) Mybpc32373InsG mice to a Western diet for 10 weeks and, in a parallel experiment, ageing them up to 18 months.
Floor W. van den Dolder, Edgar E. Nollet, Vincent A. J. Warnaar, Valentijn J. Jansen, Etto C. Eringa, Bram F. Coolen, Gustav J. Strijkers, Diederik W. D. Kuster, Jolanda van derVelden   +8 more
wiley   +1 more source

Creatine: Clinical Implications for Orthopedic Surgeons. [PDF]

Cureus
Al-Humadi S, Kohut K, Denard PJ.
europepmc   +1 more source

Preserved mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10‐day bed rest in older adults

The Journal of Physiology, Volume 604, Issue 18, Page 7772-7798, 15 September 2026.
Abstract figure legend Ten older healthy male adults underwent 10 days of bed rest. Vastus lateralis muscle biopsies were collected at baseline (PRE) and after 10 days of bed rest (BR10), and mitochondrial adaptations were assessed using an integrative approach combining respirometry, protein analyses, RNA sequencing and transmission electron ...
Evgeniia Motanova, Lucrezia Zuccarelli, Evgenii Lysenko, Stefano Amoretti, Marco Pirazzini, Ornella Rossetto, Lorenza Brocca, Roberto Bottinelli, Maria Antonietta Pellegrino, Giovanni Baldassarre, Clarissa Gissi, Giovanna Lippe, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Bruno Grassi, Marco V. Narici   +16 more
wiley   +1 more source