Results 111 to 120 of about 93,838 (303)
Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 1. Synthesis and interconversion of simple esters of ribomononucleotides [PDF]
, 1955 L. A. Heppel, Paul R. Whitfeld
openalex +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
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Medicines, 2017 Background: Phosphodiesterases (PDEs) play a major role in the regulation of cyclic adenosine monophosphate (cAMP)- and cyclic guanosine monophosphate (cGMP)-mediated pathways.
Teresa Röhrig +5 more
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Penile fracture after nerve‐sparing radical prostatectomy: Case report and review of literature
IJU Case Reports, EarlyView.Introduction Penile fractures typically do not occur in patients unable to maintain an adequate erection. Erectile dysfunction is known as one of the major complications of radical prostatectomy, and no cases of postoperative penile fractures have been reported. Case presentation A 78‐year‐old male with a history of radical prostatectomy with bilateral
Eri Fukagawa +4 more
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Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?
British Journal of Pharmacology, EarlyView., 2023 Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
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iMeta, EarlyView.This study identifies the potential quorum sensing (QS) bacteria in wastewater treatment plants (WWTPs) and constructs a QS communication network through the establishment of a local QS bacterial database with six languages and the analysis of over 1000 activated sludge microbiome samples collected from 269 WWTPs.
Yong‐Chao Wang +3 more
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Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner +10 more
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JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is characterised by immune dysregulation and skin‐barrier dysfunction, which can predispose to microbial dysbiosis and skin infections. Fungi, particularly Malassezia, are common skin colonisers in AD patients and may exacerbate the condition.
Luis F. Andrade +8 more
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JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understanding of the management of mild‐to‐moderate AD with topical treatments by examining the practices of ...
Lawrence F. Eichenfield +14 more
wiley +1 more source
Ixekizumab Type I Allergy in a Patient With Psoriasis
JEADV Clinical Practice, EarlyView.ABSTRACT A 52‐year‐old Caucasian woman was referred for an allergy workup of suspected type I allergy to the interleukin (IL)‐17A inhibitor ixekizumab. Five months after ixekizumab initiation, she suddenly developed intense pruritus and three small wheals at the injection site approximately 30 min after injection, lasting up to 3 days.
Carina Borst +2 more
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