Results 121 to 130 of about 93,838 (303)
Discovery, design, and engineering of enzymes based on molecular retrobiosynthesis
Abstract Biosynthesis—a process utilizing biological systems to synthesize chemical compounds—has emerged as a revolutionary solution to 21st‐century challenges due to its environmental sustainability, scalability, and high stereoselectivity and regioselectivity.
Ancheng Chen+5 more
wiley +1 more source
Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur+3 more
wiley +1 more source
Role of kappa‐opioid and mu‐opioid receptors in pruritus: Peripheral and central itch circuits
Abstract Modern genetic approaches in animal models have unveiled novel itch‐specific neural pathways, emboldening a paradigm in which drugs can be developed to selectively and potently target itch in a variety of chronic pruritic conditions. In recent years, kappa‐opioid receptors (KORs) and mu‐opioid receptors (MORs) have been implicated in both the ...
Brian S. Kim+5 more
wiley +1 more source
Kinetics of hydrolysis of uridylic oligonucleotides with different degree of polymerisation by snake venom phosphodiesterase [PDF]
L.B. Dolapchiev
openalex +1 more source
The triphosphoinositide phosphodiesterase of brain tissue [PDF]
W. Thompson, RMC Dawson
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ABSTRACT Background Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field‐based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement.
Mary Ni Lochlainn+4 more
wiley +1 more source
Effects of Whole-body Irradiation and Radio-mimetic Chemicals on the Acid RNAse and Phosphodiesterase Levels of Rat Intestinal Homogenate [PDF]
P.A. Gresham, W. F. R. Pover
openalex +1 more source
Abstract Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance, affecting over 50% of men aged 50 and older. ED is often linked to lifestyle factors and comorbidities, such as diabetes and cardiovascular disease.
Ahmed Ragheb
wiley +1 more source
Studies on 5'-Phosphodiesterases in Microorganisms
Akira Kuninaka+3 more
openalex +2 more sources
Abstract Atopic dermatitis, psoriasis, alopecia areata, and vitiligo have been associated with comorbid conditions, including infections, malignancies, and cardiovascular diseases. This study evaluated the prevalence and incidence rates of these comorbidities in patients from Japan.
Yue Ma+6 more
wiley +1 more source