Results 121 to 130 of about 93,838 (303)

Discovery, design, and engineering of enzymes based on molecular retrobiosynthesis

open access: yesmLife, EarlyView.
Abstract Biosynthesis—a process utilizing biological systems to synthesize chemical compounds—has emerged as a revolutionary solution to 21st‐century challenges due to its environmental sustainability, scalability, and high stereoselectivity and regioselectivity.
Ancheng Chen   +5 more
wiley   +1 more source

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

open access: yesMolecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur   +3 more
wiley   +1 more source

Role of kappa‐opioid and mu‐opioid receptors in pruritus: Peripheral and central itch circuits

open access: yesExperimental Dermatology, Volume 31, Issue 12, Page 1900-1907, December 2022., 2022
Abstract Modern genetic approaches in animal models have unveiled novel itch‐specific neural pathways, emboldening a paradigm in which drugs can be developed to selectively and potently target itch in a variety of chronic pruritic conditions. In recent years, kappa‐opioid receptors (KORs) and mu‐opioid receptors (MORs) have been implicated in both the ...
Brian S. Kim   +5 more
wiley   +1 more source

Comparing Venous vs. Capillary Blood Collection Methods for Proteomic Measurement in Peripheral Blood

open access: yesPROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Background Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field‐based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement.
Mary Ni Lochlainn   +4 more
wiley   +1 more source

Intracavernosal platelet‐rich plasma therapy for erectile dysfunction: Current evidence and future directions

open access: yesUroPrecision, EarlyView.
Abstract Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance, affecting over 50% of men aged 50 and older. ED is often linked to lifestyle factors and comorbidities, such as diabetes and cardiovascular disease.
Ahmed Ragheb
wiley   +1 more source

Studies on 5'-Phosphodiesterases in Microorganisms

open access: bronze, 1959
Akira Kuninaka   +3 more
openalex   +2 more sources

Prevalence and incidence of comorbidities in patients with atopic dermatitis, psoriasis, alopecia areata, and vitiligo using a Japanese claims database

open access: yesThe Journal of Dermatology, EarlyView.
Abstract Atopic dermatitis, psoriasis, alopecia areata, and vitiligo have been associated with comorbid conditions, including infections, malignancies, and cardiovascular diseases. This study evaluated the prevalence and incidence rates of these comorbidities in patients from Japan.
Yue Ma   +6 more
wiley   +1 more source

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