Results 161 to 170 of about 229,722 (383)

A novel two-component system contributing the catabolism of c-di-GMP influences virulence in Aeromonas veronii

open access: yesFrontiers in Microbiology
IntroductionResponse regulators from diverse two-component systems often function as diguanylate cyclases or phosphodiesterases, thereby enabling precise regulation of intracellular c-di-GMP levels to control bacterial virulence and motility.
Chaolun Liu   +7 more
doaj   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Differential Effects of Phosphodiesterase-5 Inhibitors on Hypoxic Pulmonary Vasoconstriction and Pulmonary Artery Cytokine Expression [PDF]

open access: bronze, 2005
Ben M. Tsai   +6 more
openalex   +1 more source

Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease.

open access: yesCochrane Database of Systematic Reviews, 2017
Jimmy Chong, Bonnie Leung, P. Poole
semanticscholar   +1 more source

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

open access: yesRespirology, EarlyView.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett   +6 more
wiley   +1 more source

Erectile and ejaculatory outcomes after holmium laser enucleation of the prostate: A comprehensive narrative review

open access: yesUroPrecision, EarlyView.
ABSTRACT Holmium laser enucleation of the prostate (HoLEP) has emerged as a widely adopted surgical technique for the management of benign prostatic hyperplasia (BPH), regardless of prostate size; however, its impact on male sexual function—particularly in terms of erectile and ejaculatory outcomes—remains a subject of ongoing debate.
Muhammed Arif İbiş   +5 more
wiley   +1 more source

Role of cAMP and phosphodiesterase signaling in liver health and disease.

open access: yesCellular Signalling, 2018
B. Wahlang   +3 more
semanticscholar   +1 more source

Penile traction therapy after radical pelvic surgery: Does it work?

open access: yesUroPrecision, EarlyView.
Abstract Sexual dysfunction, including erectile dysfunction and penile shortening, is a frequent consequence of radical pelvic surgeries such as prostatectomy, cystoprostatectomy, and rectal cancer surgery. These complications primarily result from nerve injury and hypoxia‐induced corporal fibrosis.
Ahmet Tevfik Albayrak   +1 more
wiley   +1 more source

Supersonic transporter (SST) deformity of penile prosthesis: Current management strategies

open access: yesUroPrecision, EarlyView.
Abstract Supersonic transporter (SST) deformity, also known as floppy glans syndrome, represents a persistent source of post‐operative dissatisfaction among patients undergoing inflatable penile prosthesis (IPP) implantation. Although infection and mechanical failure rates have declined with advances in device design and surgical technique, SST ...
Mohammed Mahdi   +2 more
wiley   +1 more source

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