Results 251 to 260 of about 96,537 (297)

Efficacy and Safety of Apremilast in Oncological Patients with Moderate-to-Severe Plaque Psoriasis: A 5 years Retrospective Observational Study. [PDF]

Clin Cosmet Investig Dermatol
Lanna C, Rivieccio A, Vultaggio M, Gaeta Shumak R, Bonacci FM, Artosi F, Borselli C, Costanza G, Bianchi L, Campione E.   +9 more
europepmc   +1 more source

New insights into interstitial cystitis/bladder pain syndrome at single‐cell resolution

BJUI Compass, Volume 6, Issue 8, August 2025.
Abstract Objective Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory bladder disorder with unknown aetiology and limited treatment options. Single‐cell RNA‐sequencing (scRNA‐seq) has provided unprecedented insights into cellular heterogeneity in IC/BPS.
Tadeja Kuret, Mateja Erdani Kreft
wiley   +1 more source

What's new in the 2025 GOLD report. [PDF]

J Bras Pneumol
Halpin DMG, Singh D.
europepmc   +1 more source

Rare Case of Laurence–Moon–Bardet–Biedl Syndrome With Pulmonary Hypertension: A Case Report

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Laurence‐Moon‐Bardet‐Biedl Syndrome is a complicated polygenic disorder that can have lethal manifestations such as pulmonary hypertension. Early recognition, comprehensive medical treatment, and psychological intervention for the family are crucial, but survival is usually short in those with a poor functional status and increasingly impaired
Areeba Mariam Mehmood, S. M. Salman Hassan, Ayesha Malik, Muhammad Faizan, Muhammad Usama bin Shabbir, Aqsa Jabeen, Allahdad Khan, Aseel Kamal   +7 more
wiley   +1 more source

Roflumilast reduces the number of lung adenocarcinomas, inflammation, and emphysema in a smoking-induced mouse model. [PDF]

BMC Pulm Med
Sakurai K, Nakayama S, Chubachi S, Otake S, Shimada T, Irie H, Tsutsumi A, Kameyama N, Hegab AE, Shimoda M, Hamamoto J, Terai H, Yasuda H, Kanai Y, Fukunaga K.   +14 more
europepmc   +1 more source

Pharmacokinetics, Bioequivalence, and Safety Studies of Crisaborole Ointment in Healthy Chinese Subjects

Clinical Pharmacology in Drug Development, Volume 14, Issue 8, Page 614-620, August 2025.
Abstract The aim of this study was to evaluate the bioequivalence and safety of a single application of crisaborole ointment to test formulation and reference formulation in healthy subjects under fasting conditions. A total of 32 subjects were included and divided into 2 groups (test‐reference; reference‐test).
Yanchao Wang, Xiaofei Zhao, Taixin Wang, Luning Xiong, Xiujuan Liu, Jing Pan, Wen Yin, Chao Zhang, Jining Dong, Kexin Zhao   +9 more
wiley   +1 more source

Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure. [PDF]

J Am Heart Assoc
Kamel R, Bourcier A, Margaria JP, Jin V, Varin A, Hivonnait A, Mercier-Nomé F, Mika D, Ghigo A, Charpentier F, Algalarrondo V, Hirsch E, Fischmeister R, Vandecasteele G, Leroy J.   +14 more
europepmc   +1 more source

PDE7 as a Precision Target: Bridging Disease Modulation and Potential PET Imaging for Translational Medicine. [PDF]

ACS Med Chem Lett
Zhao T, Liang SH.
europepmc   +1 more source

Potential of phosphodiesterase 4B inhibition in the treatment of progressive pulmonary fibrosis. [PDF]

Ther Adv Respir Dis
Keith R, Nambiar AM.
europepmc   +1 more source

Treatment Patterns of Patients With Pulmonary Hypertension: A Descriptive Study in Colombia. [PDF]

Clin Respir J
Machado-Duque M, Gaviria-Mendoza A, Valladales-Restrepo LF, Pacheco M, Franco JS, Del Rosario Forero M, Suarez R, Peñuela O, Machado-Alba JE.   +8 more
europepmc   +1 more source