Results 251 to 260 of about 225,115 (385)

Effectiveness and safety of topical phosphodiesterase 4 inhibitors in children with mild-to-moderate atopic dermatitis: A systematic review and meta-analysis. [PDF]

J Int Med Res
Wang L, Zeng L, Wu Y, Zhong M, Zhang L, Li C.   +5 more
europepmc   +1 more source

Comparison of in vivo and in vitro properties of cyclic adenosine 3':5'-monophosphate phosphodiesterase of amphibian oocytes.

, 1977
Catherine C. Allende, R Bravo, Jorge E. Allende   +2 more
openalex   +1 more source

Inhibition of adenosine 3′,5′-cyclic monophosphate phosphodiesterase [PDF]

, 1970
J. Bryan Smith, D. C. B. Mills
openalex   +1 more source

Phosphodiesterase inhibitors as therapeutics for traumatic brain injury.

Current pharmaceutical design, 2014
David J Titus, A. Oliva, N. Wilson, C. Atkins   +3 more
semanticscholar   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

British Journal of Pharmacology, EarlyView.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy, Miles J. De Blasio, Owen L. Woodman, Pasquale Maffia, Hong Yong Peh, Cheng Xue Qin   +5 more
wiley   +1 more source

Cyclic-di-GMP signalling mutants drive ecological succession and self-generated diversity in experimentally evolved biofilms of <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiology (Reading)
Wickham GJ, Zhang C, Sweet R, Solsona-Gaya M, Webber MA.   +4 more
europepmc   +1 more source

Guanylate cyclase and cyclic guanosine 3':5'-monophosphate phosphodiesterase activities and cyclic guanosine 3':5'-monophosphate levels in normal and transformed fibroblasts in culture.

, 1976
John A. Nesbitt, W. B. Anderson, Zelma Baker Miller, Ira Pastan, Tom R. Russell, D Gospodarowicz   +5 more
openalex   +1 more source

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

British Journal of Pharmacology, 2012
T. Keravis, C. Lugnier
semanticscholar   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Presence of Sildenafil and Tadalafil in Herbal Medicinal Products Claimed to Treat Erectile Dysfunction in Nyamagana and Ilemela Districts, Mwanza, Tanzania. [PDF]

Biomed Res Int
Mchallah FJ, Matinde R, Thomas A, Kihwili L, Mafuru T, Kapala J, Kimaro E, Moyo AA, Mutagwaba E, Maregesi SM.   +9 more
europepmc   +1 more source