Results 311 to 320 of about 225,115 (385)

Time to Onset of Action for Biologics and Targeted Treatments in Psoriasis: Systematic Targeted Literature Review and Network Meta-Analysis. [PDF]

Dermatol Ther (Heidelb)
Papp KA, Vender R, Purdy K, Lovegrove F, Oroz I, Grewal P, Lansang P, Park-Wyllie L, Abbarin N, Yang YW, Hooper B, Vigelis S, Disher T, Langley RG.   +13 more
europepmc   +1 more source

Isolation of Phospholipase A2 from Agkistrodon bilineatus Venom [PDF]

, 1980
Johnson, Bob D., Landberg, Karl H., Sifford, Dewey H.   +2 more
core   +2 more sources

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

Experimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings, Christopher P. Denton, Luigi Venetucci, Andrew W. Trafford   +3 more
wiley   +1 more source

The cross-regulation between two-component system BasS/BasR and c-di-GMP phosphodiesterase YfgF in biofilm formation and H₂O₂ stress response in avian pathogenic Escherichia coli. [PDF]

Poult Sci
Yu L, Wang H, Zhang X, Xue T.
europepmc   +1 more source

Sodium thiosulfate treatment rescues hyperglycaemia‐induced pronephros damage in zebrafish by upregulating nitric oxide signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott, Katrin Bennewitz, Xin Zhang, Mariia Prianichnikova, Carsten Sticht, Gernot Poschet, Jens Kroll   +6 more
wiley   +1 more source

Predicting Response to Switching From Phosphodiesterase Type 5 Inhibitor to Riociguat in Patients With Pulmonary Arterial Hypertension: Biomarker and Responder Analysis of the RESPITE and REPLACE Studies. [PDF]

Pulm Circ
Klinger JR, Al-Hiti H, Chang SA, Chang HJ, Ghofrani HA, Grünig E, Hoeper MM, Jansa P, Ota-Arakaki J, Pulido T, Simonneau G, Vizza CD, Rahner C, Meier C, Meyer G.   +14 more
europepmc   +1 more source

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

The Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder, Tomas Stary, Gergő Bitay, Norbert Nagy, Axel Loewe   +4 more
wiley   +1 more source

Anti-Inflammatory Activity of Ensifentrine: A Novel, Selective Dual Inhibitor of Phosphodiesterase 3 and Phosphodiesterase 4.

Respiration
Rheault T, Spina D, Franciosi L, Venkatasamy R, Saint DA, MacDonald-Berko M, Rheault T.   +6 more
europepmc   +1 more source

An LC-MS/MS Assay of Irsenontrine, a Novel Phosphodiesterase‑9 Inhibitor, in Human Plasma, Urine and Cerebrospinal Fluid for Application to Clinical Pharmacokinetic Studies. [PDF]

ACS Omega
Hotta K, Doda K, Aluri J, Mano Y.
europepmc   +1 more source

Glycoprotein Proteinase in Agkistrodon bilineatus Venom [PDF]

, 1980
Johnson, Bob D., Ruff, John D., Sifford, Dewey H.   +2 more
core   +2 more sources