Results 311 to 320 of about 229,722 (383)

Comparative efficacy of combination therapy including regenerative therapies versus monotherapy for erectile dysfunction: A systematic review and meta-analysis. [PDF]

Andrology
Quistini A, Fallara G, Tozzi M, Depalma M, Damiano R, Palmieri A, Castiglione F, Salonia A, Bianchi R, Ferro M, Muneer A, Alnajjar HM, Pang KH.   +12 more
europepmc   +1 more source

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Farouk Boudou, Alaeddine Berkane, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, Brian A. Murray, Mikhael Bechelany, Ahmed Barhoum   +7 more
wiley   +1 more source

Molecular characterisation of Toxoplasma gondii Mre11 reveals unique structural features and potential as a therapeutic target. [PDF]

Sci Rep
Ruiz DM, Turowski VR, Sullivan WJ, Angel SO.   +3 more
europepmc   +1 more source

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
wiley   +1 more source

Predictors of Dual Phosphodiesterase Type 5 Inhibitor Therapy in Persons With Erectile Dysfunction and Diabetes. [PDF]

Cureus
Pande A, Jha A, Chandra K, Pathak A, Kalra S.   +4 more
europepmc   +1 more source

Glycoprotein Proteinase in Agkistrodon bilineatus Venom [PDF]

, 1980
Johnson, Bob D., Ruff, John D., Sifford, Dewey H.   +2 more
core   +2 more sources

High‐Throughput Screen of NPQ in Sorghum Shows Highly Polygenic Architecture of Photoprotection

Plant-Environment Interactions, Volume 7, Issue 1, February 2026.
ABSTRACT Natural genetic variation in photosynthesis and photoprotection within crop germplasm represents an untapped resource for crop improvement. Sorghum bicolor (sorghum) is one of the world's most widely grown crops, yet the genetic basis of photoprotection in sorghum is not well understood.
Richard L. Vath, Samuel B. Fernandes, Brandon Monier, Katarzyna Głowacka, Julia Walter, Alexander E. Lipka, John Ferguson, Carl J. Bernacchi, Taylor Pederson, Johannes Kromdijk   +9 more
wiley   +1 more source

Phosphodiesterase-5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study. [PDF]

Aging Cell
Alcalde-Herraiz M, Woolf B, Xie J, Anderson E, Gill D, Tzoulaki I, Winchester LM, Yarmolinsky J, Prieto-Alhambra D, Newby D.   +9 more
europepmc   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

Pest Management Science, Volume 82, Issue 2, Page 1540-1551, February 2026.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas, Joseph Hawkins, Lauraine Swindale, Aniko Kende, John Sinclair, Jacob M Riveron, Helen Thompson, Adam Pym   +7 more
wiley   +1 more source

Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer's Disease Model. [PDF]

Cureus
Faikoglu G, Saygisever-Faikoglu K, Ozbasak H, Ugur SA, Uskur T, Akkan AG, Kelicen-Ugur P, Ozyazgan S.   +7 more
europepmc   +1 more source