Results 321 to 330 of about 229,722 (383)

Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics

Pest Management Science, Volume 82, Issue 2, Page 1668-1679, February 2026.
Microphenomics is a new technique for detecting the very early resistance of powdery mildew in wheat seedlings, after 24, 48, and 72 h from infection. A number of 29, 42, and 34 genes models were identified to harbor significant SNP markers associated with the early resistance to WPM.
Amira M.I. Mourad, Hanaa M.S. Ibrahim, Stefanie Lück, Andreas Börner, Dimitar Douchkov   +4 more
wiley   +1 more source

Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer. [PDF]

Elife
Zhang C, Zhang Z, Wu Y, Wu Y, Cheng J, Luo K, Li Z, Zhang M, Wang J, Zhang X, Li Y.   +10 more
europepmc   +1 more source

The impact of PDE5 inhibitors on cardiovascular outcomes. [PDF]

Glob Cardiol Sci Pract
Ghantous I, Tlais M, Khatib AE, Ghantous G, Maroun G, Challita A, Ayek M, Barmo G, Sahyoun M, El Kari G.   +9 more
europepmc   +1 more source

The Comparative Effectiveness of PDE5 Inhibitors and β3 Agonists Versus α-Blockers in Medical Expulsive Therapy for Distal Ureteric Stones: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Ramanah M, Banerjee I, Nunkoo S, Robinson J, Krissheeven M, Banerjee I.   +5 more
europepmc   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission-blocking target. [PDF]

FEBS Lett
Huppertz F, Caturelli MS, Lehmann LS, Kurth F, Maier AG, Matuschewski K.   +5 more
europepmc   +1 more source

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue-Related Raynaud Phenomenon in the United States. [PDF]

Arthritis Care Res (Hoboken)
Frech TM, Frech CG, Merryman WD, Sternlicht A, Baba J.   +4 more
europepmc   +1 more source

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Phosphodiesterase 4 inhibitors

Journal of the American Academy of Dermatology, 2018
Historically, drugs available for treating atopic dermatitis (AD) have been limited to topical corticosteroids and topical calcineurin inhibitors, with systemic immunosuppressants and phototherapy reserved for severe AD. Despite their efficacy and infrequent adverse events, phobia about the use of topical steroids and calcineurin inhibitors has limited
Rema, Zebda, Amy S, Paller
openaire   +3 more sources

Advances in the development of phosphodiesterase-4 inhibitors.

Journal of Medicinal Chemistry, 2020
Cyclic nucleotide phosphodiesterase 4 (PDE4) specifically hydrolyzes cyclic adenosine monophosphate (cAMP) and plays vital roles in biological processes such as cancer development. To date, PDE4 inhibitors have been widely studied as therapeutics for the
Ting Peng, Baowen Qi, Jun He, H. Ke, Jianyou Shi   +4 more
semanticscholar   +1 more source

Phosphodiesterase in Psoriasis

British Journal of Dermatology, 1969
SUMMARY. . Phosphodiesterase activity was determined by a fluorometric method using thymidine-5′-3–0-methoxy fluorescein phosphate as a substrate, in blood serum, finger-blood, normal skin, foreskin and psoriatic skin. Higher enzyme activity was found in psoriasis both in blood-serum and finger-blood in comparison with normal controls ...
F, Zaruba, M A, Karasek, E M, Farber
openaire   +2 more sources