Results 31 to 40 of about 45,588 (281)

Postoperative phosphodiesterase type 5 inhibitor administration increases the rate of urinary continence recovery after bilateral nerve-sparing radical prostatectomy [PDF]

open access: yes, 2013
To investigate the effect of phosphodiesterase type 5 inhibitor on urinary continence recovery after bilateral nerve-sparing radical prostatectomy.status ...
Briganti A   +23 more
core   +1 more source

Is phosphodiesterase type 5 inhibitor use associated with condom breakage? [PDF]

open access: yes, 2009
This is an open access article - Copyright © 2009 by the BMJ Publishing Group Ltd. All rights reserved.We tested the hypothesis that phosphodiesterase type 5 inhibitor (PDE5i) use would be associated with increased likelihood of condom breakage using an
Graham, C. A.   +7 more
core   +1 more source

COVID-19 and phosphodiesterase enzyme type 5 inhibitors

open access: yesJournal of Microscopy and Ultrastructure, 2020
COVID-19 pathology is mainly associated to a pulmonary disease which sometimes might result in an uncontrollable storm related to inflammatory diseases which could be fatal. It is well known that phosphodiesterase enzyme type 5 inhibitors (PDE5Is), such as sildenafil, have been successfully developed for the treatment of pulmonary arterial hypertension;
Al-Kuraishy, Hayder M.   +5 more
openaire   +3 more sources

Why humans need type 5 phosphodiesterase inhibitors [PDF]

open access: yesInternational Journal of Andrology, 2005
SummaryErectile dysfunction (ED) is a widespread medical condition affecting millions of males at any age and requiring medical treatment. ED may simply reflect a limit of human physiology, yet ED equates to genetic death and the high prevalence of ED is a clear evolutionary paradox.
CELLERINO, Alessandro, JANNINI E. A.
openaire   +3 more sources

A Detailed Analysis of the Association Between Postoperative Phosphodiesterase Type 5 Inhibitor Use and the Risk of Biochemical Recurrence After Radical Prostatectomy [PDF]

open access: yes, 2015
A recent study reported a detrimental effect of phosphodiesterase type 5 inhibitors (PDE5-Is) on biochemical recurrence (BCR) after radical prostatectomy (RP) for prostate cancer (PCa). We tested the association between PDE5-I use, PDE5-I therapy scheme,
Suardi N   +6 more
core   +3 more sources

Effects of the phosphodiesterase type-5 inhibitor tadalafil on nociception, morphine analgesia and tolerance in rats [PDF]

open access: yes, 2018
Aim: Tadalafil is a potent, selective and reversible inhibitor of phosphodiesterase type 5 (PDE5) enzyme breakdowning cyclic guanosine monophosphate (cGMP).
Yasar Tastemur   +9 more
core   +2 more sources

Comprehensive stability-indicating method development of Avanafil Phosphodiesterase type 5 inhibitor using advanced Quality-by-Design approach

open access: yesJournal of Analytical Science and Technology, 2020
Avanafil (AV) is the phosphodiesterase (PDE) type 5 inhibitor drug used in erectile dysfunction, having pyrrolidine, pyrimidine, carboxamide, and chlorine as functional groups which can easily break by environmental changes and cause toxicity. Henceforth,
Mital Patel, Charmy Kothari
doaj   +1 more source

The blue pill (sildenafil) and its descendants: an overview

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2017
An increasing number of men around the world suffer from erectile dysfunction (ED). Indeed, according to the sexuality study conducted by Professor Izdebski, 1 out of 10 men in Poland suffers from ED.
Krzanowski Tomasz   +3 more
doaj   +1 more source

Inadvertent antihypertensive double dosing with concurrent Tadalafil use - A double whammy on the optic nerve!

open access: yesIndian Journal of Ophthalmology. Case Reports, 2022
Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common acute unilateral optic neuropathy in adults over the age of 50. Nocturnal hypotension has been hypothesized as the potential cause of NAION.
Samuel A Minaker, Arun N E Sundaram
doaj   +1 more source

Treatment satisfaction among men with concurrent benign prostatic hyperplasia and erectile dysfunction treated with tadalafil or other phosphodiesterase type-5 inhibitor combinations. [PDF]

open access: yesPatient Prefer Adherence, 2016
Lulu K Lee,1 Amir Goren,1 Natalie N Boytsov,2 Craig F Donatucci,2 Kevin T McVary3 1Health Outcomes Practice, Kantar Health, New York, NY, 2US Real World Outcomes Research, Eli Lily & Company, Indianapolis, IN, 3Division of Urology, Southern Illinois
Lee LK   +4 more
europepmc   +2 more sources

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