Results 41 to 50 of about 45,588 (281)

Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells

open access: yesBiology Open, 2020
Cystic fibrosis (CF) is a genetic disease characterized by progressive lung and chronic digestive manifestations. We have shown that therapeutic doses of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, corrects CF Transmembrane conductance ...
Barbara Dhooghe   +7 more
doaj   +1 more source

Phosphodiesterase Type-5 Inhibitor and Oxidative Stress

open access: yesInternational Journal of Immunopathology and Pharmacology, 2008
Erectile dysfunction (ED) is a common medical condition that affects the sexual life of millions of men worldwide. Numerous physical and psychological factors are involved in normal erectile function, including neurological, vascular, hormonal and cavernous functions.
SPERANZA, Lorenza   +7 more
openaire   +3 more sources

Portopulmonary hypertension practice patterns after liver transplantation

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose   +3 more
wiley   +1 more source

REVITALISE: A Large Observational Study Assessing the Safety and Effectiveness of Vardenafil in Men With Erectile Dysfunction and Metabolic Syndrome

open access: yesSexual Medicine, 2016
Introduction: Erectile dysfunction (ED) is prevalent in men with metabolic syndrome (MetS); therefore, it is important to characterize ED treatments in this population.
Ridwan Shabsigh, MD, FACS   +1 more
doaj   +1 more source

Erectile dysfunction - an update of current practice and future strategies [PDF]

open access: yes, 2013
Erectile dysfunction (ED) is defined as the inability to achieve and maintain a penile erection adequate for satisfactory sexual intercourse.1 Up to 150 million men worldwide suffer from ED and this figure is likely to double by the year 2025.2 A number
Asif Muneer   +3 more
core   +1 more source

A Randomised, Double-Blinded, Placebo-Controlled Study of the Phosphodiesterase Type 5 Inhibitor Sildenafil for the Treatment of Preeclampsia [PDF]

open access: yes, 2009
Objective: To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. Methods: Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly ...
Howe, David   +6 more
core   +1 more source

Efficacy and safety of mirodenafil, A new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction [PDF]

open access: yes, 2018
Introduction. Mirodenafil is a newly developed oral phosphodiesterase type 5 inhibitor, currently under investigation as a treatment for erectile dysfunction (ED). Aim.
정우식
core   +1 more source

Effectiveness of sildenafil in pulmonary hypertension secondary to mitral valve disease

open access: yesArchives of Medicine and Health Sciences, 2020
Background and Aim: Pulmonary arterial hypertension almost always accompanies long-standing mitral valvular heart disease. The objective of this study is to study the effectiveness of sildenafil in reducing pulmonary hypertension in the peroperative and ...
Tinni Mitra   +4 more
doaj   +1 more source

Is Li-ESWT effective in diabetic patients with severe erectile dysfunction?

open access: yesAsian Journal of Andrology, 2022
Noninvasive low-intensity extracorporeal shockwave treatment (Li-ESWT) has been widely used to treat erection disorders. There is no clear information regarding either the selection of patients for the treatment or the treatment protocol.
Müslüm Ergün, Osman Akyüz
doaj   +1 more source

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