Results 171 to 180 of about 67,560 (281)

The safety and efficacy of phosphodiesterase type 5 inhibitors in the treatment of diabetic erectile dysfunction: a systematic review and meta-analysis. [PDF]

PeerJ
Zhu Z, Xu J, Dai B, Lin M, Yang H, Liu S, Bao P, Nan Z.   +7 more
europepmc   +1 more source

Short-term outcomes of phosphodiesterase type 5 inhibitors for fetal growth restriction: a study protocol for a systematic review with individual participant data meta-analysis, aggregate meta-analysis, and trial sequential analysis. [PDF]

Syst Rev, 2021
Liauw J, Groom K, Ganzevoort W, Gluud C, McKinlay CJD, Sharp A, Mackay L, Kariya C, Lim K, von Dadelszen P, Limpens J, Jakobsen JC, STRIDER Consortium.   +12 more
europepmc   +1 more source

Cost comparison of phosphodiesterase type 5 inhibitors: rural vs urban New York State counties and online pharmacies. [PDF]

Sex Med
Di Scipio SM, Katz A.
europepmc   +1 more source

Sodium thiosulfate treatment rescues hyperglycaemia‐induced pronephros damage in zebrafish by upregulating nitric oxide signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott, Katrin Bennewitz, Xin Zhang, Mariia Prianichnikova, Carsten Sticht, Gernot Poschet, Jens Kroll   +6 more
wiley   +1 more source

Phosphodiesterase type 5 inhibitors combined with traditional Chinese medicine for diabetes mellitus-induced erectile dysfunction: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Xiang L, Liu A, Tang W, Sun B, Yang Y, Li Y, Chen S, Zhao J, Zhang W, Cai X, Tang X.   +10 more
europepmc   +1 more source

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

The Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder, Tomas Stary, Gergő Bitay, Norbert Nagy, Axel Loewe   +4 more
wiley   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats

The Journal of Physiology, EarlyView.
Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe, Audrys Pauza, Olivia M. S. Gold, Xin Shen, Fernanda Brognara, Rosanna Roberts Nonu, Dylan K. Pen, Aabharika Bose, Emma N. Bardsley, Anna P. Ponnampalam, Davi J. A. Moraes, Julian F. R. Paton   +11 more
wiley   +1 more source

Utilization Trends of Phosphodiesterase Type-5 Inhibitors for Erectile Dysfunction Between 2019 and 2023 in Tanzania. [PDF]

Cureus
Sangeda RZ, Kadinde AW, Masatu CF, Mwalwisi YH, Yahya-Malima KI, Fimbo AM.   +5 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease: A Cohort Study. [PDF]

Neurology
Adesuyan M, Jani YH, Alsugeir D, Howard R, Ju C, Wei L, Brauer R.   +6 more
europepmc   +1 more source