Results 151 to 160 of about 38,631 (238)

Revisiting Controversial Areas in the Management of Premature Ejaculation

Trends in Urology &Men's Health, Volume 17, Issue 4, August 2026.
ABSTRACT The cause of premature ejaculation (PE) is often multifactorial in nature, and effective management of PE is complex and should involve multimodal approaches. This narrative review examines the ongoing controversies surrounding key areas in the diagnosis and treatment of PE with an emphasis on future research directions to align clinical care ...
Dong Sup Lee, Min Gu Park, Sun Tae Ahn, Ho Seok Chung, Hwancheol Son, Hyun Jun Park, Eric Chung   +6 more
wiley   +1 more source

Phosphodiesterase type 5 inhibitors do not prevent curvature progression but shorten pain duration in the active phase of Peyronie's Disease: A retrospective cohort study. [PDF]

Int J Impot Res
Durukan E, Kraglund R, Rashid SA, Thorkilgaard T, Jensen CFS, Fode M.   +5 more
europepmc   +1 more source

Ejaculatory Dysfunction and Minimally Invasive Surgical Treatments (MIST) for Male Lower Urinary Tract Symptoms Secondary to Benign Prostatic Enlargement

Trends in Urology &Men's Health, Volume 17, Issue 4, August 2026.
ABSTRACT While transurethral resection of the prostate (TURP) is considered the standard surgical treatment in symptomatic benign prostatic enlargement (BPE) secondary to benign prostatic hyperplasia (BPH), it is not without surgical morbidities and has adverse impact on various sexual function domains such as ejaculatory dysfunction (EjD) and erectile
Haijun Yao, Tao Wang, Shan‐Chao Zhao, Lei Zheng, Rui Jiang, Han Wu, Jingjing Gao, Baibing Yang, Yuzhuo Yang, Haocheng Lin, Eric Chung   +10 more
wiley   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, Volume 183, Issue 16, Page 4761-4777, August 2026.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source

Long-term effectiveness and predictors of success of low-intensity shockwave therapy in phosphodiesterase type 5 inhibitors non-responders. [PDF]

Arab J Urol, 2020
Musa ZS, El-Assmy A, Shokry AM, Shokeir AA, Zween T, Al-Kenawy MR.   +5 more
europepmc   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

The Role of Water in Protein–Ligand Binding: Decisive Factor, Annoying Feature, or Indispensable Control Element: In Any Case, a Major Challenge

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Water influences ligand binding to a protein. Replacing, picking up, or modulating water dynamics restructures the water arrangement and affects the enthalpic and entropic signatures of binding. Whether the two properties add up or cancel each other out determines the expected ligand affinity enhancement.
Gerhard Klebe
wiley   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, Volume 13, Issue 38, 9 July 2026.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, Volume 13, Issue 39, 13 July 2026.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, Volume 78, Issue 7, Page 1535-1553, July 2026.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source