The Effect of Phosphodiesterase-type 5 Inhibitors on Erectile Function: An Overview of Systematic Reviews [PDF]
Frontiers in Pharmacology, 2021 Background: Multiple systematic reviews explore the effect of phosphodiesterase type 5 (PDE5) inhibitors on erectile dysfunction (ED), with each study addressing specific outcomes.
Nikolaos Pyrgidis +12 more
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Phosphodiesterase Type 5 Inhibitors in Male Reproduction: Molecular Mechanisms and Clinical Implications for Fertility Management [PDF]
CellsPhosphodiesterases, particularly the type 5 isoform (PDE5), have gained recognition as pivotal regulators of male reproductive physiology, exerting significant influence on testicular function, sperm maturation, and overall fertility potential.
Aris Kaltsas +4 more
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Phosphodiesterase type 5 inhibitors as treatment for erectile dysfunction: a webinar-based poll unveiling perceptions of healthcare professionals [PDF]
Journal of Comparative Effectiveness ResearchAim: Erectile dysfunction (ED) is marked by a recurring incapacity to achieve or uphold a satisfactory erection during sexual activities. The study aims to increase awareness about male reproductive health, dispel misconceptions about ED and encourage ...
Maher S Moazin +10 more
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A role for phosphodiesterase type 5 inhibitors in remodelling the urinary bladder after radiation exposure. [PDF]
PLoS ONE, 2020 Minimizing the toxicity of radiotherapy is challenging. We investigated the effects of a phosphodiesterase type-5 inhibitor (PDE5I) on the urinary bladder after pelvic radiotherapy.
Hee Youn Kim, Dong Sup Lee
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Rapid Screening and Quantitative Determination of Illegal Phosphodiesterase Type 5 Inhibitors (PDE-5i) in Herbal Dietary Supplements [PDF]
Journal of Analytical Methods in Chemistry, 2021 Phosphodiesterase type 5 inhibitors (PDE-5i) are the first-line medication for oral erectile dysfunction, which are used according to the prescription of doctors. However, these substances have been found illegally in supplementary foods. The quality and
Thi Oanh Nguyen +10 more
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Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling [PDF]
Frontiers in Oncology, 2020 Combination therapies that display cancer-killing activities through either coexistent targeting of several cellular factors or more efficient suppression of a specific pathway are generally used in cancer treatment.
Jui-Ling Hsu +7 more
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Phosphodiesterase type 5 inhibitors after left ventricular assist device: no free lunch? [PDF]
ESC Heart Failure, 2021 E. Wilson Grandin, Jeffrey J. Teuteberg
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Efficacy of phosphodiesterase type 5 inhibitors in univentricular congenital heart disease: the SV‐INHIBITION study design [PDF]
ESC Heart Failure, 2020 Aims In univentricular hearts, selective lung vasodilators such as phosphodiesterase type 5 (PDE5) inhibitors would decrease pulmonary resistance and improve exercise tolerance.
Pascal Amedro +18 more
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AB030. Evolution of phosphodiesterase type 5 inhibitors [PDF]
Transl Androl Urol, 2016 After launching of sildenafil citrate, the last invention of 20(th) century, in 1998, oral phosphodiesterase type 5 (PDE5) inhibitor has been established as first line treatment of erectile dysfunction and shift new paradigm of diagnosis and treatment of erectile dysfunction.
europepmc +3 more sources
Phosphodiesterase Type 5 Inhibitors and COVID-19: Are They Useful In Disease Management? [PDF]
The World Journal of Men's Health, 2020 Nicola Mondaini
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