Results 201 to 210 of about 69,283 (286)
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Sildenafil helps the beat go on
Experimental Physiology, EarlyView.
Jules C. Hancox
wiley +1 more source
Single‐cell analysis reveals neuroprotective histone deacetylase inhibitor pathways
Abstract INTRODUCTION Alzheimer's disease (AD) involves β‐amyloid (Aβ) accumulation, tau pathology, and neuroinflammation, driving cognitive decline. Despite extensive research, disease‐modifying therapies remain elusive. We integrated single‐cell RNA sequencing (scRNA‐seq), spatial transcriptomics, and in vitro validation to identify repurposable ...
Madeline Peyton +12 more
wiley +1 more source
Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database
Abstract Objective The purpose of this study is investigate the clinical outcomes of men with benign prostatic hyperplasia (BPH) and bladder stones treated concomitantly with Aquablation and bladder stone removal in an international, multi‐institutional cohort.
Joshua D. Cabral +25 more
wiley +1 more source
Abstract Objectives The objective of this study is to evaluate the safety and efficacy of Rezūm water vapour energy therapy (WAVE) in Japanese patients with benign prostatic hyperplasia (BPH) continuing antithrombotic therapy and to validate the Okayama University Modified Clavien‐Dindo classification (OU‐mCD) for perioperative hematuria.
Takatoshi Moriwake +13 more
wiley +1 more source
Notes on Three Palustrine Natural Community Types in the Arkansas Ozarks [PDF]
Orzell, Steve L. +2 more
core +2 more sources
The Vascular‐Immune Cells Crosstalk and Microenvironment in Pulmonary Hypertension
This review synthesizes current evidence showing how vascular–immune cell crosstalk and microenvironmental cues shape pulmonary vascular remodeling in pulmonary hypertension. We provide an integrative perspective that positions disrupted cellular communication as a central driver of disease progression and a promising source of future therapeutic ...
Lola Navarro‐Llinares +3 more
wiley +1 more source
Defining the Efficacy and Safety of Phosphodiesterase Type 5 Inhibitors with Tamsulosin for the Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia with or without Erectile Dysfunction: A Network Meta-Analysis. [PDF]
Ma C, Zhang J, Cai Z, Xiong J, Li H.
europepmc +1 more source
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Demonstration of a Heat-Stable Cyclic GMP Phosphodiesterase in the Medium of Physarum flavicomum [PDF]
Lynch, Thomas J., Ross, Mark S.
core +2 more sources

