Results 31 to 40 of about 3,076 (182)
Twin Theories, Polytope Mutations and Quivers for GTPs [PDF]
JHEP 2307:034,2023, 2023 We propose a unified perspective on two sets of objects that usually arise in the study of bipartite field theories. Each of the sets consists of a polytope, or equivalently a toric Calabi-Yau, and a quiver theory. We refer to the two sets of objects as original and twin.
arxiv +1 more source
EFSA Journal, Volume 21, Issue 4, April 2023., 2023 Abstract In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the risks to public health from the presence of BPA in foodstuffs and to establish a tolerable daily intake (TDI). For this re‐evaluation, a pre‐established protocol was
EFSA Panel on Food Contact Materials +37 more
wiley +1 more source
Fasting: From Physiology to Pathology
Advanced Science, Volume 10, Issue 9, March 24, 2023., 2023 Fasting is emerging as a simple but attractive strategy for fighting human diseases, including aging, cancer, neurodegenerative diseases, and metabolic disorders. This review provides an a timely overview of the role and mechanism of fasting in physiology and pathology, highlights the therapeutic potential of fasting, alone and in combination with ...
Dongmei Tang +5 more
wiley +1 more source
A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis
Cancer Communications, 2020 Highly active lipogenesis is essential for rapid tumor growth. Sterol regulatory element‐binding protein (SREBP) is a key transcriptional factor for lipogenesis and activated by reduced sterol and oxysterol levels.
Hongfei Jiang +3 more
doaj +1 more source
Nuclear Factor I Regulates Expression of the Gene for Phosphoenolpyruvate Carboxykinase (GTP) [PDF]
Journal of Biological Chemistry, 1998 Nuclear factor-I (NFI) binds to the phosphoenolpyruvate carboxykinase (GTP) (PEPCK) gene promoter immediately 5' to the cAMP regulatory element (CRE). This suggests an interaction between NFI and factors that bind the CRE. Of the four NFI isoforms expressed in mammalian tissues, NFI-A and -B stimulate basal transcription from the PEPCK gene promoter in
Ching Y. Hu +9 more
openaire +3 more sources
EMBO reports, Volume 23, Issue 10, 06 October 2022., 2022 Lint‐O, a novel L(3)mbt interactor, cooperates with L(3)mbt to suppress piRNA amplification genes and other gene targets to maintain homeostasis in Drosophila ovary and brain. Abstract Loss‐of‐function mutations in Drosophila lethal(3)malignant brain tumor [l(3)mbt] cause ectopic expression of germline genes and brain tumors.
Hitomi Yamamoto‐Matsuda +7 more
wiley +1 more source
Invertebrate Biology, Volume 141, Issue 3, September 2022., 2022 Abstract The neritid snail Theodoxus fluviatilis has formed regional subgroups in northern Europe, where it appears in both freshwater (FW) and brackish water (BW) in coastal areas of the Baltic Sea. These ecotypes show clear differences in osmotolerance and in the modes of accumulating organic osmolytes under hyperosmotic stress.
Amanda Alice Wiesenthal +3 more
wiley +1 more source
Molecular Ecology, Volume 31, Issue 11, Page 3112-3127, June 2022., 2022 Abstract The environment can alter the magnitude of phenotypic variation among individuals, potentially influencing evolutionary trajectories. However, environmental influences on variation are complex and remain understudied. Populations in heterogeneous environments might exhibit more variation, the amount of variation could differ between benign and
Richelle L. Tanner +2 more
wiley +1 more source
PROTEOMICS, Volume 22, Issue 7, April 2022., 2022 Abstract So far, mass spectrometry‐based targeted proteomics is the most sensitive approach to answer and address specific biological questions in an accurate and quantitative fashion. However, the data analysis design used for such quantification varies in the field leading to discrepancies in the reported values.
Tingting Li +2 more
wiley +1 more source
Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase [PDF]
, 2016 The cytosolic form of phosphoenolpyruvate carboxykinase (PCK1) plays a regulatory role in gluconeogenesis and glyceroneogenesis. The role of the mitochondrial isoform (PCK2) remains unclear.
Carrodeguas, J.A. +5 more
core +2 more sources