Results 41 to 50 of about 39,501 (165)

Phosphate Limitation Modulates Vibrio Cholerae Outer Membrane Vesicle Formation, Composition and Toxicity

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Vibrio cholerae inhabits phosphorus‐poor aquatic environments and host intestine, where it expresses genes regulated by the PhoB/PhoR two‐component system in response to inorganic phosphate (Pi) limitation. Like other Gram‐negative bacteria, V.
Matheus Luchetta da Fonseca, Livia Carvalho Barbosa, Beatriz Ferreira de Carvalho Patricio, Wellington da Silva Ferreira, Carolina Neumann Keim, Cedric Delporte, Pierre van Antwerpen, Jean‐Marie Ruysschaert, Paulo Mascarello Bisch, Wanda Maria Almeida von Kruger   +9 more
wiley   +1 more source

A physiology study of Escherichia coli overexpressing phosphoenolpyruvate carboxykinase [PDF]

, 2008
To determine whether intracellular ATP levels can be affected, Escherichia coli overexpressing phosphoenolpyruvate carboxykinase (pck) or phosphoenolpyruvate carboxylase (ppc) were grown in glucose minimal medium.
Kim, Pil, Lee, Sang Yup, Kwon, Yeong-Deok   +2 more
core   +1 more source

Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes

Journal of Biological Chemistry, 1993
The hormonal regulation of transcription of the phosphoenolpyruvate carboxykinase (GTP) (4.1.1.32) (PEPCK) gene during diabetes was studied using transgenic mice containing a chimeric gene consisting of segments of the PEPCK promoter (-2000/+73, -460/+73, -355/+73) linked to bovine growth hormone (bGH) reporter gene.
J E, Friedman, J S, Yun, Y M, Patel, M M, McGrane, R W, Hanson   +4 more
openaire   +2 more sources

Roles of Asp75, Asp78, and Glu83 of GTP-dependent Phosphoenolpyruvate Carboxykinase from Mycobacterium smegmatis [PDF]

Journal of Biological Chemistry, 2006
The roles of Asp(75), Asp(78), and Glu(83) of the (75)DPSDVARVE(83) element of Mycobacterium smegmatis GTP-dependent phosphoenolpyruvate (PEP) carboxykinase (GTP-PEPCK) were investigated. Asp(78) and Glu(83) are fully conserved in GTP-PEP-CKs. The human PEPCK crystal structure suggests that Asp(78) influences Tyr(220); Tyr(220) helps to position bound ...
Christopher L, Case, Edward M, Concar, Kristin L, Boswell, Biswarup, Mukhopadhyay   +3 more
openaire   +2 more sources

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Fruit respiration: putting alternative pathways into perspective

New Phytologist, Volume 250, Issue 1, Page 54-73, April 2026.
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez, Sergio García‐Carbonell, Alisdair R. Fernie, Marta Pujol, Igor Florez‐Sarasa   +4 more
wiley   +1 more source

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way [PDF]

, 2010
Background The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle type has a specific composition and distribution of the four fiber types. To find novel
Boekschoten, M.V., Mariman, E.C.M., Egbert Smit, Hulshof, M.F., Wilde, J., de, Edwin CM Mariman, Smit Egbert, Mark V Boekschoten, de Wilde, J., Janneke de Wilde, Mariman Edwin CM, de Groot, P.J., de Wilde Janneke, de Groot Philip, Smit, E., Philip de Groot, Groot, P.J., de, Boekschoten Mark V, Martijn FM Hulshof, Hulshof Martijn FM, Hulshof, M.F.M., de Groot, P.   +21 more
core   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

SREBP-1c and Sp1 Interact to Regulate Transcription of the Gene for Phosphoenolpyruvate Carboxykinase (GTP) in the Liver [PDF]

Journal of Biological Chemistry, 2004
The sterol regulatory element-binding protein-1c (SREBP-1c), as well as SREBP-1a and SREBP-2, inhibit transcription of the gene encoding the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C). There are two SREBP regulatory elements (SREs) in the PEPCK-C gene promoter (-322 to -313 and -590 to -581).
Kaushik, Chakravarty, Shwu-Yuan, Wu, Cheng-Ming, Chiang, David, Samols, Richard W, Hanson   +4 more
openaire   +2 more sources

Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis

, 1972
The de novo synthesis of glucose in mam-malian liver involves a number of enzymatic reactions, some specific to this process and others acting in reverse of their role in gly-colysis (Fig. 1).
Richard W. Hanson, Alan J. Garber
core   +1 more source