Results 61 to 70 of about 10,168 (226)

Which way does the citric acid cycle turn during hypoxia? The critical role of alpha-ketoglutarate dehydrogenase complex [PDF]

, 2013
The citric acid cycle forms a major metabolic hub and as such it is involved in many disease states involving energetic imbalance. In spite of the fact that it is being branded as a "cycle", during hypoxia, when the electron transport chain does not ...
Chinopoulos Christos
core   +1 more source

The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism – insights from mathematical modeling [PDF]

, 2016
Background Adaptation of the cellular metabolism to varying external conditions is brought about by regulated changes in the activity of enzymes and transporters.
Berndt, Nikolaus, Bulik, Sascha, Holzhuetter, Hermann-Georg   +2 more
core   +1 more source

Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments. [PDF]

, 2015
Weight gain is a major health problem among psychiatric populations. It implicates several receptors and hormones involved in energy balance and metabolism.
Aubry, J.M., Castelao, E., Choong, E., Conus, P., Delacrétaz, A., Eap, C.B., Gholamrezaee, M., Kutalik, Z., Magistretti, P., Preisig, M., Quteineh, L., Saigi-Morgui, N., Vandenberghe, F., Vollenweider, P., von Gunten, A., Waeber, G.   +15 more
core   +2 more sources

Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M [PDF]

, 2021
Background: Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the decarboxylation of oxaloacetate to phosphoenolpyruvate. The mitochondrial isozyme, PEPCK-M is highly expressed in cancer cells, where it plays a role in nutrient stress response. To date,
Abás Prades, Sònia, Aragó, Marc, Brea, José, Carrodeguas, Jose A., Escolano Mirón, Carmen, Figueras, Agnes, Galdeano, Carlos, García-Roves, Pablo M. (Pablo Miguel), Ginex, Tiziana, Hyrossová, Petra, Latorre, Pedro, Loza, María Isabel, Luque Garriga, F. Xavier, Moreno Felici, Juan, Perales Losa, Carlos, Pérez, Belén, Rodríguez Arévalo, Sergio, Viñals Canals, Francesc   +17 more
core   +1 more source

Actinomyces spp. gene expression in root caries lesions [PDF]

, 2016
Background: studies of the distribution of Actinomyces spp. on carious and non-carious root surfaces have not been able to confirm the association of these bacteria with root caries, although they were extensively implicated as a prime suspect in root ...
Damé-Teixeira, N, Devine, DA, Do, T, Maltz, M, Parolo, CCF, Tugnait, A   +5 more
core   +2 more sources

Combined transcriptomic-(1)H NMR metabonomic study reveals yhat monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes [PDF]

, 2011
Adipose tissue is a major storage site for lipophilic environmental contaminants. The environmental metabolic disruptor hypothesis postulates that some pollutants can promote obesity or metabolic disorders by activating nuclear receptors involved in the ...
Beale E. G., Beale E. G., Becker K., Beckonert O., Berman T., Cadoudal T., Cadoudal T., Chakravarty K., Chantal Benelli, Christianson J. L., Chui P. C., Claude Forest, Claus S. P., Cloarec O., Desvergne B., Durmaz E., Ellero S. L., Eriksson L., Eubank D. W., Feige J. N., Feige J. N., Franck Letourneur, Franckhauser S., Fukuwatari T., Gregoire F. M., Grun F., Grun F., Guan H. P., Hanson R. W., Hanson R. W., Hatch E. E., Huang da W., Huber W. W., Hurst C. H., Isabelle de Waziers, Martinelli M. I., Millward C. A., Mullerova D., Nicolas Cagnard, Okuno A., Philippe H. Beaune, Rink J. D., Roberts L. D., Roberts R. A., Sandrine Ellero-Simatos, Sandrine P. Claus, Sears D. D., Si Y., Stahlhut R. W., Su X., Targett-Adams P., Tordjman J., Trygg J., Tusher V. G., van Harmelen V., Veselkov K. A., Weuve J., Yoo H., Zancanaro C., Zhang Y. H.   +59 more
core   +2 more sources

Changes in the microsomal proteome of tomato fruit during ripening [PDF]

, 2019
The variations in the membrane proteome of tomato fruit pericarp during ripening have been investigated by mass spectrometry-based label-free proteomics.
De Lorenzo, Giulia, Fabbri, Claudia, Licursi, Valerio, Mattei, Benedetta, Negri, Rodolfo, Pontiggia, Daniela, Spinelli, Francesco   +6 more
core   +1 more source

Nitrogen recycling from the xylem in rice leaves: dependence upon metabolism and associated changes in xylem hydraulics [PDF]

, 2016
Measurements of amino acids in the guttation fluid and in the xylem exudates of cut leaves from intact plants provide evidence of the remarkable efficiency with which these nitrogenous compounds are reabsorbed from the xylem sap. This could be achieved
Engelsberger, Ewers, Gaspar, Gerrard Wheeler, Hacke, Hayakawa, Jomain-Baum, Karen J. Bailey, Leegood, Mae, Nolte, Richard C. Leegood, Sakurai, Walker, Walker   +14 more
core   +1 more source

Macrophage phenotype in response to ECM bioscaffolds [PDF]

, 2017
Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular ...
Badylak, Stephen F, Bartolacci, Joseph G., Brown, Bryan N., Cramer, Madeline C., Dziki, Jenna L., Huleihel, Luai, LoPresti, Samuel T., Rausch, Theresa, Scarritt, Michelle E., Swinehart, Ilea T., Vorobyov, Tatiana, White, Lisa J.   +11 more
core   +2 more sources

Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.

Journal of Biological Chemistry, 1990
Vanadate, at concentrations between 0.5 and 2 mM, rapidly decreased the basal level of P-enolpyruvate carboxykinase (GTP) (EC 4.1.1.32) mRNA and blocked the dibutyryl cyclic AMP (Bt2cAMP)-induced increase in enzyme mRNA in both FTO-2B and H4IIE rat hepatoma cells.
Bosch i Tubert, Fàtima, Hatzoglou, Maria, Park, Edwards A., Hanson, Richard W.   +3 more
openaire   +4 more sources