Influence of Temperature on the Catalytic Function of Phosphoenolpyruvate Carboxykinase [PDF]
, 2019 Enzymes are well known for their importance in biological systems. One of these enzymes, PEPCK, has been well studied and characterized over the years.
Morrow, Benjamin
core
Discovery of PPi-type Phosphoenolpyruvate Carboxykinase Genes in Eukaryotes and Bacteria [PDF]
, 2015 Phosphoenolpyruvate carboxykinase (PEPCK) is one of the pivotal enzymes that regulates the carbon flow of the central metabolism by fixing CO2 to phosphoenolpyruvate (PEP) to produce oxaloacetate or vice versa.
Chiba Yoko +5 more
core +1 more source
Advances and Applications in Bioinformatics and Chemistry, 2019 Luiz Phillippe R Baptista,1 Vanessa VC Sinatti,1 Joao HM Da Silva,2 Laurent Emmanuel Dardenne,3 Ana Carolina Guimarães11Laboratory for Functional Genomics and Bioinformatics, Fiocruz, Oswaldo Cruz Institute, Rio de Janeiro, RJ, Brazil; 2Group for ...
Baptista LPR +4 more
doaj
The effect of in vivo PBDE treatment on hepatic phosphoenolpyruvate carboxykinase (PEPCK) enzyme kinetics in male Wistar rats [PDF]
, 2011 Polybrominated diphenyl ethers (PBDEs) are synthetic flame-retardant chemicals that enter the environment and mammalian body and may disrupt glucose metabolism.
Nash, Jessica T
core +1 more source
Developmental acquisition of DNase I sensitivity of the phosphoenolpyruvate carboxykinase (GTP) gene in rat liver. [PDF]
Proceedings of the National Academy of Sciences, 1987 The sensitivity to DNase I digestion of the gene encoding rat phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) was assessed during development and prior to the onset of expression. This gene is resistant to DNase I digestion in nuclei isolated from livers of 19-day rat fetuses.
Nissim Benvenisty, Lea Reshef
openaire +3 more sources
Gravitational Thomas Precession - A Gravitomagnetic Effect ? [PDF]
arXiv, 2003 Gravitational Thomas Precession (GTP) is the name given to the Thomas Precession when the acceleration is caused by a gravitational force field. In continuation of our discussion on the idea of a GTP, in this note by way of considering the motion of a planet around the Sun, the GTP is shown to be a gravitomagnetic effect that a planet might experience ...
arxiv
Which way does the citric acid cycle turn during hypoxia? The critical role of alpha-ketoglutarate dehydrogenase complex [PDF]
, 2013 The citric acid cycle forms a major metabolic hub and as such it is involved in many disease states involving energetic imbalance. In spite of the fact that it is being branded as a "cycle", during hypoxia, when the electron transport chain does not ...
Chinopoulos Christos
core +1 more source
Trans regulation of the phosphoenolpyruvate carboxykinase (GTP) gene, identified by deletions in chromosome 7 of the mouse. [PDF]
Proceedings of the National Academy of Sciences, 1986 Livers from newborn mice homozygous for either one of the lethal deletions c14CoS or c3H in chromosome 7 have drastically reduced levels of cytosolic phosphoenolpyruvate carboxykinase (GTP) [GTP:oxaloacetate carboxy-lyase (transphosphorylating), EC 4.1.1.32] activity when compared with normal littermates.
Kenneth S. Krauter +6 more
openaire +3 more sources
Structure-guided Inhibitor Design of Mycobacterium Tuberculosis Drug Targets from Central Carbon Metabolism [PDF]
, 2020 A key determinant of the pathogenicity of M. tuberculosis (Mtb) is its ability to conserve energy and resources by altering its intermediate metabolism response to host-derived hostile conditions.
Kim, Haelee
core
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability [PDF]
, 2018 Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate.
Hyroššová, Petra +4 more
core +1 more source