Results 61 to 70 of about 60,616 (293)

Escherichia coli Phosphoenolpyruvate Carboxylase [PDF]

Journal of Biological Chemistry, 1971
Abstract Phosphoenolpyruvate carboxylase of Escherichia coli was purified to homogeneity. The molecular weight of the native protein, as determined by sedimentation equilibrium analyses, is 402,000. Sedimentation equilibrium analyses on the enzyme denatured in 3.5 m, 5 m, and 7 m guanidine hydrochloride gave a single species with a molecular weight of ...
openaire   +2 more sources

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

Phosphoenolpyruvate carboxylase (PEPC) is essential for the glycolytic pathway and parasite proliferation in Babesia gibsoni

Animal Diseases
Apicomplexan parasites predominantly generate ATP and lactic acid through glycolysis and anaerobic glucose metabolism, incorporating CO2 into glycolysis via a stage-dependent phosphoenolpyruvate carboxylase (PEPC) mechanism.
Dong-Fang Li, Ling-Na Wang, Yi-Dan Bai, Yu-Xin Yu, Xing Lu, Xing-Ai Guan, Fang-Jie Li, Sen Wang, Lan He, Jun-Long Zhao   +9 more
doaj   +1 more source

Multiple conformations in solution of the maize C4-phosphoenolpyruvate carboxylase isozyme

Heliyon, 2021
The photosynthetic phosphoenolpyruvate carboxylase isozyme from C4 plants (PEPC-C4) has a complex allosteric regulation, involving positive cooperativity in binding the substrate phosphoenolpyruvate as well as positive and negative allosteric effectors ...
Fátima Barreda-Huerta, Ismael Bustos-Jaimes, Carlos Mújica-Jiménez, Rosario A. Muñoz-Clares   +3 more
doaj  

Enhanced tolerance to drought in transgenic rice plants overexpressing C4 photosynthesis enzymes

Crop Journal, 2013
Maize-specific pyruvate orthophosphate dikinase (PPDK) was overexpressed in rice independently or in combination with the maize C4-specific phosphoenolpyruvate carboxylase (PCK). The wild-type (WT) cultivar Kitaake and transgenic plants were evaluated in
Jun-Fei Gu, Ming Qiu, Jian-Chang Yang
doaj   +1 more source

Effects of Phosphorylation on Phosphoenolpyruvate Carboxykinase from the C4 Plant Guinea Grass [PDF]

, 2002
In the C4 plant Guinea grass (Panicum maximum), phosphoenolpyruvate carboxykinase (PEPCK) is phosphorylated in darkened leaves and dephosphorylated in illuminated leaves.
Acheson, R.M., Chen, Z., Leegood, R.C., Walker, R.P.   +3 more
core   +1 more source

Multiple isoforms of phosphoenolpyruvate carboxylase in the Orchidaceae (subtribe Oncidiinae): implications for the evolution of crassulacean acid metabolism

Journal of Experimental Botany, 2014
Summary Multiple isoforms of phosphoenolpyruvate carboxylase genes were sequenced from related orchid species with distinct photosynthesic types. Phylogenetic analysis indicated that CAM-associated isoforms originated from gene duplications and adaptive ...
K. Silvera, K. Silvera, K. Winter, B. L. Rodriguez, Rebecca L. Albion, J. Cushman   +5 more
semanticscholar   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Positive selection of Kranz and non-Kranz C4 phosphoenolpyruvate carboxylase amino acids in Suaedoideae (Chenopodiaceae)

Journal of Experimental Botany, 2014
Summary Phylogenetic analysis of independent gains of C4 photosynthesis in Suaedoideae shows differences compared with other C4 lineages in amino acids of phosphoenolpyruvate carboxylase under positive selection and their position relative to functional ...
J. Rosnow, G. Edwards, E. Roalson
semanticscholar   +1 more source

Oat Bran Supplementation Improves Glucose Metabolism, Food Addiction, and Gut Microbiota in Rats With High‐Fat Diet‐Induced Obesity

Food Frontiers, EarlyView.
ABSTRACT Oat bran (OB), a byproduct of the oat milling process, is a nutrient‐dense cereal cultivated in cool, dry mountainous regions and is known for its potential health benefits. To explore its obesity‐alleviating effects and the underlying mechanisms, we examined the influence of OB on glucose metabolism, appetite‐regulating hormones, gut ...
Xue Bai, Meili Zhang, Yakun Zhang, Yuanyuan Zhang, Rui Huo, Qixin Gu, Ying Miao   +6 more
wiley   +1 more source