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Comparative Analysis of Classic Semen Extenders for Frozen-Thawed Boar Semen. [PDF]
Kong Y+7 more
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The crucial role of metabolic reprogramming in driving macrophage conversion in kidney disease. [PDF]
Gong N+8 more
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The role of phosphofructokinase P in hypertrophy of iPSC-derived human cardiomyocytes
Katarzyna Kmiotek+5 more
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MdbHLH3 modulates apple soluble sugar content by activating phosphofructokinase gene expression
Journal of Integrative Plant Biology, 2022Sugars are involved in plant growth, fruit quality, and signaling perception. Therefore, understanding the mechanisms involved in soluble sugar accumulation is essential to understand fruit development.
Kai-di Gu, Cui-hui Sun, Da-gang Hu
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Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations
Phosphofructokinase-1 (PFK1), the ‘gatekeeper’ of glycolysis, catalyses the committed step of the glycolytic pathway by converting fructose-6-phosphate to fructose-1,6-bisphosphate. Allosteric activation and inhibition of PFK1 by over ten metabolites and
Bradley A Webb+2 more
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PHOSPHOFRUCTOKINASE: STRUCTURE AND CONTROL [PDF]
Phosphofructokinase from Bacillus stearothermophilus shows cooperative kinetics with respect to the substrate fructose-6-phosphate (F6P), allosteric activation by ADP, and inhibition by phosphoenolpyruvate. The crystal structure of the active conformation of the enzyme has been solved to 2.4 A resolution, and three ...
Philip R. Evans+2 more
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Background: V-ATPase proton pumps are regulated by glucose. The glycolytic enzyme phosphofructokinase-1 binds to V-ATPase. Results: Mutant phosphofructokinase-1 (pfk1Δ and pfk2Δ) cannot acidify the vacuoles, although V-ATPases are competent to transport ...
Karlett J Parra
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