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Metabolic hijacking styles: a review of how viral life cycles dictate glucose metabolism reprogramming. [PDF]
Front MicrobiolBie Z, Tan Y, Ye C, Wei K.
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Muscle Phosphofructokinase Deficiency
Archives of Neurology, 1967The clinical hallmarks of muscle phosphorylase deficiency (McArdle's disease) are muscle cramps and exercise intolerance, contracture following ischemic work, and episodic myoglobinuria. We have encountered a patient with all these symptoms who proved to lack muscle phosphofructokinase (PFK) rather than phosphorylase.
R B, Layzer, L P, Rowland, H, Ranney
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Muscle Phosphofructokinase Deficiency
Archives of Neurology, 1973The sixth case, to our knowledge, of phosphofructokinase deficiency is reported in a 20-year-old, otherwise healthy, man. The clinical presentation consisted of exercise intolerance, muscle pain, and elevated blood levels of muscle enzymes. The abnormality in the muscle was confirmed with electromyography, ischemic exercise testing, light microscopy ...
W E, Tobin +3 more
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Cold labile phosphofructokinase
Biochemical and Biophysical Research Communications, 1971Abstract Phosphofructokinase from chicken liver undergoes reversible inactivation at low temperature. The rate of the inactivation increases with decrease in temperature. The cold inactivation is stimulated by monovalent anions or ATP, but prevented by polyvalent anions or fructose 1,6-di-P. Results of sucrose density gradient centrifugation indicate
N, Kono, K, Uyeda
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PHOSPHOFRUCTOKINASE: STRUCTURE AND CONTROL
Biochemical Society Transactions, 1981Phosphofructokinase from Bacillus stearothermophilus shows cooperative kinetics with respect to the substrate fructose-6-phosphate (F6P), allosteric activation by ADP, and inhibition by phosphoenolpyruvate. The crystal structure of the active conformation of the enzyme has been solved to 2.4 A resolution, and three ...
P R, Evans, G W, Farrants, P J, Hudson
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Lithium inhibition of phosphofructokinase
Journal of Inorganic Biochemistry, 1981The mode of action of lithium in prophylaxis of recurrent affective disorder is unknown although it has been suggested that lithium might compete with magnesium in magnesium dependent processes. We have previously shown pyruvate kinase to be inhibited by lithium and the present study demonstrates a small inhibition by lithium of phosphofructokinase ...
P K, Kajda, N J, Birch
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PFKP: More than phosphofructokinase
2023Phosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions.
Haizhen, Wang +3 more
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