Results 121 to 130 of about 31,695 (232)

Crystal structure of Thermus caldophilus phosphoglycerate kinase in the open conformation

, 2006
Phosphoglycerate kinase (PGK) is a key glycolytic enzyme that catalyzes the reversible transfer of a phosphate from 1,3-bisphosphoglycerate to ADP to form 3-phosphoglycerate and ATP in the presence of magnesium.
Dooil Kim, Y J Im, Jungdon Bae, Dae Sil Lee, G B Kang, Eom, Soo Hyun, Lee, Jun Hyuck, Kang, Gil Bu, M K Kim, Bae, Jungdon, Kim, Mun-Kyoung, J H Lee, Im, Young Jun, Kim, Dooll, S H Eom, Lee, Dae-Sil   +15 more
core   +1 more source

PPT1‐mediated plastidic phosphoenolpyruvate import enhances fatty acid biosynthesis in sugar‐rich tissues

New Phytologist, Volume 250, Issue 6, Page 3900-3913, June 2026.
Summary Metabolic engineering of vegetative tissues for lipid production holds transformative potential for sustainable biofuels, yet achieving sufficient yields remains challenging. Here, we present a strategy to enhance fatty acid synthesis by redirecting cytosolic phosphoenolpyruvate (PEP) into plastids through overexpression of the plastidial ...
Jiang Wang, Yi‐Hsuan Lin, Xueyi Xue, Gabriel Beuchat, Yaxin Li, Jiankun Li, Li‐Qing Chen   +6 more
wiley   +1 more source

PERSPECTIVE: organelle positioning as a principle of metabolic regulation and stress tolerance

The Plant Journal, Volume 126, Issue 6, June 2026.
SUMMARY Plants have evolved elaborate acclimation strategies to withstand adverse environments, involving all levels of their function and organization. While macroscopic movements through differential growth that enable the physical re‐shaping and ‐positioning of organs have been a major field of study, the highly active dynamics of cell organelles ...
Alisdair R. Fernie, Guillaume Decros, Jan Multhoff, Jana Sippel, Jan‐Ole Niemeier, Pedro Barreto, Arun Sampathkumar, Uwe Sonnewald, Markus Schwarzländer   +8 more
wiley   +1 more source

Hypoxic‐hypocapnic red blood cells in PAGGSM additive solution before and after gamma irradiation show improved metabolism

Vox Sanguinis, Volume 121, Issue 6, Page 801-808, June 2026.
Abstract Background and Objectives Hypoxic/hypocapnic (HH) treatment and storage conditions have been shown to reduce oxidative stress and improve red blood cell (RBC) quality. This study aimed to validate a good manufacturing practice HH RBC product for obtaining the licence for routine use in patients, by comparison with normoxic RBCs both without ...
Soroth Chey, Jacqueline Maier, Samuel Sowemimo‐Coker, Reinhard Henschler   +3 more
wiley   +1 more source

Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex.

, 1978
The mouse autosomal locus that determines the form of phosphoglycerate kinase found only in testes is shown here to be closely linked to but not included within the major histocompatibility complex on chromosome 17.
Eicher, E M, Flaherty, L, Cherry, M
core  

Phosphoglycerate Kinase 2 (PGK2) Is Essential for Sperm Function and Male Fertility in Mice

, 2010
Phosphoglycerate kinase 2 (PGK2), an isozyme that catalyzes the first ATP-generating step in the glycolytic pathway, is encoded by an autosomal retrogene that is expressed only during spermatogenesis.
Goulding, Eugenia H., O'Brien, Deborah A., Danshina, Polina V., Dai, Qunsheng, Geyer, Christopher B., Eddy, E. M., McCarrey, John R., Willis, William D., Kitto, G. Barrie   +8 more
core   +1 more source

PKM2 functions as a histidine kinase to phosphorylate PGAM1 and increase glycolysis shunts in cancer

The EMBO Journal
Phosphoglycerate mutase 1 (PGAM1) is a key node enzyme that diverts the metabolic reactions from glycolysis into its shunts to support macromolecule biosynthesis for rapid and sustainable cell proliferation.
Yang Wang, Hengyao Shu, Yanzhao Qu, Xin Jin, Jia Liu, Wanting Peng, Lihua Wang, Miao Hao, Mingjie Xia, Zhexuan Zhao, Kejian Dong, Yao Di, Miaomiao Tian, Fengqi Hao, Chaoyi Xia, Wenxia Zhang, Xueqing Ba, Yunpeng Feng, Min Wei   +18 more
doaj   +1 more source

Phosphoglycerate-kinase-1 Is a Potential Prognostic Biomarker in HNSCC and Correlates With Immune Cell Infiltration. [PDF]

Cancer Genomics Proteomics, 2023
Wang P, Wang YY, Xu YL, Zhang CY, Wang K, Wang Q.   +5 more
europepmc   +1 more source

The use of phase combination in the refinement of phosphoglycerate kinase at 2.5 A resolution

, 1981
The combination of phase information obtained by the method of isomorphous replacement with that calculated from a partial model of the structure has proved to be a powerful tool in the interpretation of the structure of horse muscle phosphoglycerate ...
Rice, D.W.
core   +1 more source

Conformational dynamics in phosphoglycerate kinase, an open and shut case?

, 2013
Domain motions are essential to many catalytic mechanisms in enzymes but they are often difficult to study. X-ray crystal structures can provide molecular details of snapshots of catalysis but many states important in the cycle remain inaccessible using ...
Bowler, Matthew W.
core   +1 more source