Results 261 to 270 of about 27,020 (299)

ChemInform Abstract: Phosphoinositide‐Regulated Kinases and Phosphoinositide Phosphatases

ChemInform, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Nick R. Leslie, Ricardo M. Biondi, Dario R. Alessi   +2 more
openaire   +1 more source

Phosphoinositide Contributions

Science, 2012
The phospholipid phosphatidylinositol 4-phosphate defines important physical properties of the cell membrane.
openaire   +2 more sources

The ubiquitous phosphoinositides

Biochemical Society Transactions, 2004
There are now known to exist seven phosphoinositides all derived through various metabolic routes from the parent lipid phosphatidylinositol. With one additional metabolite, diacylglycerol, these represent a rich resource of bioactive lipids responsible for recruiting protein effectors and marking membrane compartments.
openaire   +3 more sources

Phosphoinositide signalling in Drosophila

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015
Phosphoinositides (PtdInsPs) are lipids that mediate a range of conserved cellular processes in eukaryotes. These include the transduction of ligand binding to cell surface receptors, vesicular transport and cytoskeletal function. The nature and functions of PtdInsPs were initially elucidated through biochemical experiments in mammalian cells. However,
Sruthi S, Balakrishnan, Urbashi, Basu, Padinjat, Raghu   +2 more
openaire   +2 more sources

Phosphoinositide metabolism and oncogenes

Clinica Chimica Acta, 1989
The hydrolysis of phosphatidylinositol 4,5-bisphosphate plays important roles in growth factor- or oncogene-induced cell proliferation. However, it is still unknown whether the hydrolysis of phosphatidylinositol 4,5-bisphosphate is an essential step for cell growth. To solve this problem, we developed a monoclonal antibody against the lipid.
T, Takenawa, K, Fukami
openaire   +2 more sources

Pathways for phosphoinositide synthesis

Chemistry and Physics of Lipids, 1999
In eukaryotic cells, phosphatidylinositol can be phosphorylated on the inositol ring by a series of kinases to produce at least seven distinct phosphoinositides. These lipids have been implicated in a variety of cellular processes, including calcium regulation, actin rearrangement, vesicle trafficking, cell survival and mitogenesis.
K F, Tolias, L C, Cantley
openaire   +2 more sources

Phosphoinositides and Cellular Pathogens

2012
Phosphoinositides are considered as highly dynamic players in the spatiotemporal organization of key signaling pathways, actin cytoskeleton rearrangements, establishment of cell polarity and intracellular vesicle trafficking. Their metabolism is accurately controlled and mutations in several phosphoinositide metabolizing enzymes take part in the ...
Payrastre, Bernard, Gaits-Iacovoni, Frédérique, Sansonetti, Philippe, Tronchère, Hélène   +3 more
openaire   +2 more sources

Phosphoinositides

2012
Anne M. Heacock, Stephen K. Fisher
  +4 more sources

Phosphoinositide-Regulated Kinases and Phosphoinositide Phosphatases

Chemical Reviews, 2001
N R, Leslie, R M, Biondi, D R, Alessi
openaire   +2 more sources

Receptor-Mediated Phosphoinositide Metabolism

1987
In a scant few years, the ligand-stimulated turnover of phosphatidylinositol (PI) has progressed from a curious observation to a major biochemical and pharmacological enterprise. In the 1940’s, de Hevesy (see de Hevesy, 1964) introduced the use of beta-emitting radioisotopes to biochemistry, and demonstrated that the addition of 32P-labeled inorganic ...
openaire   +2 more sources