Results 261 to 270 of about 27,357 (285)

Evaluating the impact of leniolisib treatment on symptoms and health-related quality of life in activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome

Vinay Rao, Allison Morgan, Troy R. Torgerson, Amanda Harrington, John Whalen, Ewen Munro, Jo Luscombe, Anna de la Motte, Beverly Romero, Roxana Bahar, Jason Bradt   +10 more
openalex   +1 more source

A cell-permeable fluorescent probe reveals temporally diverse PI(4,5)P2 dynamics evoked by distinct GPCR agonists in neurons. [PDF]

Chem Sci
Kundu R, Mondal S, Kapadia A, Banerjee AA, Kucherak OA, Klymchenko AS, Koushika SP, Venkatramani R, Vaidya VA, Datta A.   +9 more
europepmc   +1 more source

Optimizing PH Domain-Based Biosensors for Improved Plasma Membrane PIP₃ Measurements in Mammalian Cells. [PDF]

Cells
Damouni A, Tóth DJ, Schönek A, Kasbary A, Boros AP, Várnai P.   +5 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics. [PDF]

FEBS Lett
Bancilhon MD, Mesmin B.
europepmc   +1 more source

The Use of Synaptic Extracellular Myo-Inositol to Treat Developmental and Epileptic Encephalopathy. [PDF]

Ann Child Neurol Soc
Vos EN, Demirbas D, Rodan L, Yang E, Prabhu SP, Chen J, Huang X, Qi W, Haynes RL, Lehtinen MK, Bennett MJ, He M, Pearl PL, Rubio-Gozalbo ME, Poduri A, Berry GT.   +15 more
europepmc   +1 more source

Pediatric and Adolescent Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS): Demographic and Clinical Findings from the APDS-Characterization and Clinical Outcomes Immunologic Registry (APDS-CHOIR)

Nicholas L. Rider, Manish J. Butte, Jason Raasch, Kelli Wong Williams, Nicholas Hartog, Valeria Duran, Joseph Harper   +6 more
openalex   +1 more source

Phosphoinositides as membrane organizers

Nature Reviews Molecular Cell Biology, 2022
Phosphoinositides are signalling lipids derived from phosphatidylinositol, a ubiquitous phospholipid in the cytoplasmic leaflet of eukaryotic membranes. Initially discovered for their roles in cell signalling, phosphoinositides are now widely recognized ...
York Posor, Wonyul Jang, Volker Haucke
exaly   +2 more sources

Targeted Phosphoinositides Analysis Using High-Performance Ion Chromatography-Coupled Selected Reaction Monitoring Mass Spectrometry

Journal of Proteome Research, 2021
Phosphoinositides are minor components of cell membranes, but play crucial roles in numerous signal transduction pathways. To obtain quantitative measures of phosphoinositides, sensitive, accurate, and comprehensive methods are needed. Here, we present a
Albert Sickmann, Johan W.M. Heemskerk, Philipp Westhoff   +2 more
exaly   +2 more sources

Phosphoinositides: Regulators of membrane traffic and protein function [PDF]

FEBS Letters, 2007
Phosphoinositides serve as important spatio-temporal regulators of intracellular trafficking and cell signalling events. In addition to their recognition by specific phosphoinositide binding domains present within cytoplasmic adaptor proteins or membrane
Michael Krauss, Volker Haucke
exaly   +2 more sources

Dynamic control of neuroexocytosis by phosphoinositides in health and disease

Progress in Lipid Research, 2011
Phosphoinositides are a group of phospholipids whose inositol headgroups can be phosphorylated at three distinct positions thereby generating seven different isotypes. The conversion between these lipid species depends on the activity of specific sets of
Frederic A Meunier
exaly   +2 more sources