Results 161 to 170 of about 369,030 (389)

The Inner Nuclear Membrane Has a Unique Lipid Signature

BioEssays, EarlyView.
The inner nuclear membrane (INM) has a distinct lipid profile, most notably characterized by high enrichment of phosphatidylserine (PS). In this review, Yang Niu and Tamas Balla summarize recent advances in elucidating the INM's lipid composition and related metabolic pathways, while elaborating further on their potential functional roles.
Yang Niu, Tamas Balla
wiley   +1 more source

Phospholipase B in snake venoms and bee venom [PDF]

, 1964
HM Doery, JE Pearson
openalex   +1 more source

All Organisms Can Be Anesthetized, but There's No Point?

BioEssays, EarlyView.
ABSTRACT Because of their interest in medicine, most studies on anesthesia have historically focused on the nervous systems of animals. This has often led to the neglect of the fact that all life forms have the potential to be anesthetized. Anesthetics target proteins, such as four‐domain voltage‐dependent Na+/Ca2⁺ channels (4D‐NaV/CaV) and glutamate ...
Lucia Sylvain‐Bonfanti, Delphine Arbelet‐Bonnin, Christophe Lalanne, Olivier Dellis, Patrice Meimoun, Patrick Laurenti, Etienne Grésillon, François Bouteau   +7 more
wiley   +1 more source

Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

Molecular Oncology, 2019
The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator.
Silke Reinartz, Sonja Lieber, Jelena Pesek, Dominique T. Brandt, Alina Asafova, Florian Finkernagel, Bernard Watzer, Wolfgang Andreas Nockher, Andrea Nist, Thorsten Stiewe, Julia M. Jansen, Uwe Wagner, Anne Konzer, Johannes Graumann, Robert Grosse, Thomas Worzfeld, Sabine Müller‐Brüsselbach, Rolf Müller   +17 more
doaj   +1 more source

The Hydrolysis of Unimolecular Films of 32P-Labelled Lecithin, Phosphatidylethanolamine and Phosphatidylinositol with Phospholipase A (Naja naja Venom) [PDF]

, 1966
R. M. C. Dawson
openalex   +1 more source

Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye, Marisa A. Jones, Georgeen Gaza‐Bulseco, Carmelata Chitikila, Severine Clavier, Delphine Fougeron, Christine Grimaldi, Karen Hurkmans, Richard Hutchinson, Brenda Kellogg, Xinrong Liu, Nisha Palackal, Mahima Tank, Pascal Valax, Thomas Waerner, Fengqiang Wang, Ying Zhang, Yiwei Zhao, Sapphire Sloan, Christina Zuch de Zafra   +19 more
wiley   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core  

M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy.

New England Journal of Medicine, 2009
L. Beck, R. Bonegio, G. Lambeau, David M. Beck, D. Powell, Timothy D. Cummins, J. Klein, D. Salant   +7 more
semanticscholar   +1 more source

Enzymes Produced by a Pseudomonas Species Which Inactivate Inhibitors of Certain Viral Hemagglutinins. I. Identification and Purification of a Proteinase and Phospholipase C [PDF]

, 1969
Nathalie J. Schmidt, Pinkie S. Gee, Juanita Dennis, Edwin H. Lennette   +3 more
openalex   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source