Results 191 to 200 of about 187,280 (259)

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

The Phospholipase A₂ Superfamily in Health and Disease: From Lipid Signaling to Inflammation, Cancer, and Neurodegeneration. [PDF]

J Lipid Atheroscler
Sikder MM, Labony SA.
europepmc   +1 more source

Safety evaluation of the food enzyme phospholipase D from the genetically modified <i>Streptomyces violaceoruber</i> strain pPDN. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Chesson A, Aguilera J, Andryszkiewicz M, Cavanna D, Kovalkovicova N, Liu Y, di Piazza G, de Sousa RF.   +20 more
europepmc   +1 more source

Proteomic profiling and comparative hemotoxicity of <i>Gloydius brevicaudus</i> and <i>Deinagkistrodon acutus</i> venoms: insights into functional convergence. [PDF]

J Venom Anim Toxins Incl Trop Dis
Hu J, Guo H, Wang N, Cai X.
europepmc   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Endometritis and endometrial fibrosis are associated with alterations in mare endometrial proteome. [PDF]

BMC Vet Res
Leal M, Silva E, Alpoim-Moreira J, Pinto-Bravo P, Rebordão MR, Quaresma M, Jalali B, Molcan T, Szóstek-Mioduchowska A, Skarzynski D, Ferreira-Dias G.   +10 more
europepmc   +1 more source

Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aims Weight loss after metabolic bariatric surgery (MBS) is heterogeneous, and the contribution of liver histology and genetic susceptibility to insufficient weight loss (IWL) or weight regain (WR) remains unclear. We assessed the prevalence of IWL and WR after MBS and their association with liver histology and metabolic ...
Felice Cinque, Marica Meroni, Sara Badiali, Miriam Longo, Erika Paolini, Elisa Galfrascoli, Giovanna Oberti, Giuseppina Pisano, Gabriele Maffi, Matteo Mureddu, Elena Corbetta, Valentina Scimè, Emma Calzavara, Francesca Alletto, Annalisa Cespiati, Luigi Boni, Anna Ludovica Fracanzani, Paola Dongiovanni, Rosa Lombardi   +18 more
wiley   +1 more source

Exploratory proteomic characterization of <i>Apis mellifera</i> venom across an environmental gradient in central Chile. [PDF]

Front Pharmacol
Marcos JL, Campos-Soto R, Ortiz R, Olivares Y, Villena J, Párraga M, Sotomayor-Zárate R, Constandil L, Müller H.   +8 more
europepmc   +1 more source

Role of protein kinase C in the release of arachidocic acid from platelets

, 1999
MACCHIONI, Lara, NARDICCHI, Vincenza, GORACCI, Gianfrancesco, GRESELE, Paolo, NUCCIARELLI, FABIO, PORCELLATI, Serena   +5 more
core  

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source