Results 211 to 220 of about 187,280 (259)

Topical formulation of repurposed FDA-approved compounds inhibits Pseudomonas aeruginosa ExoU and improves corneal infection outcomes. [PDF]

PLoS Pathog
Foulkes DM, Fernig DG, McLean K, Held M, Harris JA, Sun Y, Fothergill JL, Price V, Byrne DP, Czanner G, Tam C, Kaye SB.   +11 more
europepmc   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

Journal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos, Magda Feres, William V. Giannobile, Hatice Hasturk, Egija Zaura   +4 more
wiley   +1 more source

Effect of sequential laboratory passaging on virulence factors traits and antifungal susceptibility variation in Candida albicans clinical isolates. [PDF]

BMC Microbiol
Nouraei H, Yousefi Z, Zareshahrabadi Z, Amirzadeh N, Rajabi SZ, Pakshir K.   +5 more
europepmc   +1 more source

Obesity Modifies Sphingolipid Signatures in Childhood Asthma

Clinical &Experimental Allergy, EarlyView.
Harshita Shailesh, Alaa Abdelhamid, Ahmed Arabi, Yaman Al‐Haneedi, Shana Jacob, Giridhara Rathnaiah Babu, Stefan Worgall, Ibrahim Janahi   +7 more
wiley   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Machine learning-based MPO and Lp-PLA2 profiling reveals asthma-predominant inflammatory signature in asthma-COPD overlap. [PDF]

World Allergy Organ J
Liu M, Chen J, Yao J, Zheng Y, Li X, Zhong H, Liu J, Zheng J, Ye R, Huang H, Zheng P, Sun B.   +11 more
europepmc   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

A Pseudoenzymatic Regulatory Role of the Noncatalytic Subunit of the Neurotoxin Vipoxin at Arachidonic-Acid-Containing Membrane Interfaces. [PDF]

Membranes (Basel)
Petrova S, Mircheva K, Sotirovska E, Grozev NA, Mladenova KS, Videv P, Doumanov J, Balashev K.   +7 more
europepmc   +1 more source

Multiplex FAD2/FATB Editing Generates Ultra‐High‐Oleic, Low‐Saturate Soybean With Increased Seed Fatty Acid Content

Plant Biotechnology Journal, EarlyView.
ABSTRACT Oleic acid (18:1), saturated fatty acid (SFA), and polyunsaturated fatty acid (PUFA) levels are important traits for storage stability and edibility. In this study, we aimed to develop high‐oleic soybean (Glycine max) by simultaneously targeting fatty acid desaturase 2 (FAD2) and fatty acyl‐ACP thioesterase B (FATB) gene families using CRISPR ...
Won Nyeong Kim, Yu‐Ri Choi, Hye Jeong Kim, Young‐Soo Chung, Hyun Uk Kim   +4 more
wiley   +1 more source