Results 251 to 260 of about 369,030 (389)

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

A Pomegranate Polyphenol Extract Suppresses the Microbial Production of Proatherogenic Trimethylamine (TMA) in an In Vitro Human Colon Model

open access: yesMolecular Nutrition &Food Research, EarlyView.
Trimethylamine N‐oxide (TMAO) is associated with various cardiometabolic and other diseases and can cause thrombosis and vascular inflammation. Dietary l‐carnitine and choline are metabolized by gut microbiota to trimethylamine (TMA), which is oxidized to TMAO in the liver.
Julia E. Haarhuis   +6 more
wiley   +1 more source

Postprandial Metabolism, Inflammation, and Plasma Bile Acid Kinetics in a Rat Model: Implications for Translational Research

open access: yesMolecular Nutrition &Food Research, EarlyView.
Sprague‐Dawley rats were used to investigate postprandial metabolic and inflammatory responses following the consumption of an energy‐dense meal. Time‐resolved plasma and liver analyses revealed fluctuations in bile acid levels, particularly cholic acid, along with changes in metabolic intermediates, oxylipins, and inflammatory markers.
Larissa Rodrigues   +8 more
wiley   +1 more source

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