Results 41 to 50 of about 369,030 (389)
International Journal of Molecular Sciences, 2011 Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire +2 more sources
Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation [PDF]
, 2013 Acknowledgments: We thank Dr. Robert Barkley and Charis Uhlson for mass spectrometry analysis. Funding: This work was supported by grants from the National Institutes of Health HL34303 (to C.C.L., R.C.M. and D.L.B), DK54741 (to J.V.B.), GM5322 (to D.L.W.)
Bonventre, Joseph V. +9 more
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Frontiers in Immunology, 2018 Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important ...
Vittorio Caprio +15 more
doaj +1 more source
Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications [PDF]
, 2019 Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation and fibrillation makes ...
Alza, Natalia Paola +4 more
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Ezrin-related phosphoinositide pathway modifies RhoA and Rac1 in human osteosarcoma cell lines [PDF]
, 2015 Selected Phosphoinositide-specific Phospholipase C (PI-PLC) enzymes occupy the convergence point of the broad range of pathways that promote Rho and Ras GTPase mediated signalling, which also regulate the activation of ezrin, a member of the ezrin ...
DELLA ROCCA, Carlo +2 more
core +1 more source
Phosphoinositide-specific phospholipase C in health and disease
Journal of Lipid Research, 2015 Phospholipases are widely occurring and can be found in several different organisms, including bacteria, yeast, plants, animals, and viruses. Phospholipase C (PLC) is a class of phospholipases that cleaves phospholipids on the diacylglycerol (DAG) side ...
L. Cocco, M. Follo, L. Manzoli, P. Suh
semanticscholar +1 more source
PLoS Pathogens, 2015 The coordinated exit of intracellular pathogens from host cells is a process critical to the success and spread of an infection. While phospholipases have been shown to play important roles in bacteria host cell egress and virulence, their role in the ...
P. Burda +5 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2020 DDHD1 and DDHD2 are both intracellular phospholipases A1 and hydrolyze phosphatidic acid in vitro. Given that phosphatidic acid participates in neurite outgrowth, we examined whether DDHD1 and DDHD2 regulate neurite outgrowth.
Yuki Maemoto +8 more
doaj +1 more source
Enzymatic Degumming of Rice Bran Oil Using Different Commercial Phospholipases and Their Cocktails
Life, 2021 Rice bran oil is a highly nutritious vegetable oil, as it is rich in tocols and γ-oryzanol. Degumming is the first step in the vegetable oil refining process, and its main objective is the removal of phospholipids or gums. In the present study, enzymatic
Mayara S. Rodrigues +7 more
doaj +1 more source
Activation of phospholipase C beta4 by heterotrimeric GTP-binding proteins [PDF]
, 1994 Transient transfection assays were used to determine how the activity of phospholipase C beta 4, which is preferentially expressed in retina, was regulated.
Jiang, Huiping +2 more
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