Results 91 to 100 of about 296,459 (243)

Activation of phospholipase C beta4 by heterotrimeric GTP-binding proteins [PDF]

open access: yes, 1994
Transient transfection assays were used to determine how the activity of phospholipase C beta 4, which is preferentially expressed in retina, was regulated.
Jiang, Huiping   +2 more
core  

Effects of omega-3 fatty acids on arterial stiffness in patients with hypertension: a randomized pilot study. [PDF]

open access: yes, 2015
BackgroundOmega-3 fatty acids prevent cardiovascular disease (CVD) events in patients with myocardial infarction or heart failure. Benefits in patients without overt CVD have not been demonstrated, though most studies did not use treatment doses (3.36 g)
Beaty, Brenda   +5 more
core   +1 more source

Apolipoprotein B exhibits phospholipase A1 and phospholipase A2 activities

open access: yesFEBS Letters, 1993
Low density lipoproteins (LDL) as well as isolated apolipoprotein B (ApoB) have been shown to exhibit phospholipase A2 (PLA2) activity toward phospholipids containing an oxidized or short fatty acyl chain at position 2. Some of these studies employed the fluorescent analogue of phosphatidyl choline (PC), C6‐NBD‐PC, containing NBD‐caproic acid (C6‐NBD ...
Reisfeld, Nurit   +3 more
openaire   +2 more sources

The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells

open access: yesmBio
Contact-dependent hemolysins are virulence factors in a number of human pathogens, including Helicobacter pylori, Rickettsia typhi, Bartonella bacilliformis, Mycobacterium tuberculosis, entero-invasive Escherichia coli, and Shigella.
Michael A. Apicella   +6 more
doaj   +1 more source

The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells [PDF]

open access: yes, 1992
Thyrotropin-releasing hormone stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) in GH3 cell membranes. The stimulation of the phosphoinositide phospholipase C (PI/PLC) activity can be blocked by incubation of GH3 membranes with ...
Aragay, Anna M.   +2 more
core  

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

open access: yes, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio   +5 more
core   +2 more sources

The Utility of the Lipoprotein-Associated Phospholipase A (Lp-PLA) Assay in Detecting Abnormalities in Lipid Metabolism and Cardiovascular Risk in an HIV-Infected South African Cohort

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
People with HIV (PWH) have an increased prevalence of cardiovascular disease (CVD) compared to uninfected patients. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) catalyzes the synthesis of pro-inflammatory lipids that recruit monocytes.
Elizabeth S. Mayne MD   +7 more
doaj   +1 more source

Enhancement of Sphingosine 1-Phosphate-Induced Phospholipase C Activation During G0-G1 Transition in Rat Hepatocytes

open access: yesJournal of Pharmacological Sciences, 2004
We previously reported that sphingosine 1-phosphate (S1P) induces inhibition of adenylyl cyclase and activation of phospholipase C via independent G protein-coupled receptors in adult rat hepatocytes.
Dong-Soon Im   +4 more
doaj   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

open access: yes, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

Phospholipases in Food Industry: A Review

open access: yes, 2012
Mammal, plant, and mainly microbial phospholipases are continuously being studied, experimented, and some of them are even commercially available at industrial scale for food industry. This is because the use of phospholipases in the production of specific foods leads to attractive advantages, such as yield improvement, energy saving, higher efficiency,
Casado, Víctor   +3 more
openaire   +3 more sources

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