Results 121 to 130 of about 114,080,691 (261)
Health Care Science, EarlyView.This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying +6 more
wiley +1 more source
Oncogenic action of phospholipase A2 in prostate cancer
, 2006 Mortality from prostate cancer is a result of progression of cancer cells to become androgen-refractory and metastatic. Eicosanoid products of the cyclooxygenase (COX) and lipoxygenase (LOX) pathways are important mediators of the proliferation of ...
Sved, Paul +8 more
core +1 more source
Lipid signalling in plant development and responses to environmental stresses
Frontiers in Plant Science, 2016 Eric eRuelland +2 more
doaj +1 more source
Cysteine Biosynthesis Controls Serratia marcescens Phospholipase Activity
, 2017 Serratia marcescens causes health care-associated opportunistic infections that can be difficult to treat due to a high incidence of antibiotic resistance. One of the many secreted proteins of S. marcescens is the PhlA
Harry L. T. Mobley +2 more
core +1 more source
Phospholipase A2 Enzymes: A Multidisciplinary Approach to Studying the Mechanisms of Activation and Inhibition [PDF]
, 2017 Phospholipase A2 is a superfamily of enzymes that play a major role in cellular homeostasis and disease development. This class of enzymes acts on a diverse set of phospholipids substrates, often releasing products that have a role in inflammatory ...
Vasquez, Alexis Marie
core
, 2004 Phospholipase D catalyses the hydrolysis of the phosphodiester bond of glycerophospholipids to generate phosphatidic acid and a free headgroup. Phospholipase D activities have been detected in simple to complex organisms from viruses and bacteria to ...
McDermott, Mark +2 more
core +1 more source
Kidney kallikrein and phospholipase activities in Milan spontaneously hypertensive rats.
, 1979 Renal kallikrein and phospholipase activities were evaluated in a strain of spontaneously hypertensive rats developed by Dr. Bianchi in Milan (MHR).
PICCOLI, ANTONIO +3 more
core
Plant phospholipase A: Advances in molecular biology, biochemistry and cellular functions
, 2013 Plant phospholipase As (PLAs) are a complex group of enzymes that catalyze the release of free fatty acids from phospholipids. Plant PLAs can be grouped into three families, PLA1, PLA2, and patatin-like PLA, that catalyze the hydrolysis of acyl groups ...
Weselake, Randall J +2 more
core +1 more source
The genetic and functional basis of three inherited cutaneous and gastrointestinal diseases in humans [PDF]
, 2014 This thesis describes investigations into the genetic basis and pathophysiology of three distinct inherited diseases in humans, two of which are strongly associated to the function of the ectodomain sheddase enzyme ADAM17.
Brooke, Matthew A
core
Phospholipase A2 isoforms in acute pancreatitis.
, 2001 OBJECTIVE To assess phospholipase A2 isoforms during human and experimental acute necrotizing pancreatitis. Phospholipase A2 isoforms (group I, II, and IV) were examined in acute pancreatitis tissues in humans and rats to determine whether the exocrine ...
Zimmermann A +7 more
core +1 more source