Results 31 to 40 of about 114,080,691 (261)

Phospholipase C-η2 interacts with nuclear and cytoplasmic LIMK-1 during retinoic acid-stimulated neurite growth [PDF]

, 2015
We gratefully acknowledge financial support from the Wellcome Trust (Grant No. WT089803MA to J.M.L.) and the School of Medicine, University of St Andrews.Neurite growth is central to the formation and differentiation of functional neurons and recently ...
Mohammed Arastoo, John M. Lucocq, Hacker, Christian, Lucocq, John Milton, Arastoo, Mohammed, Popovics, Petra, Stewart, Alan J., Christian Hacker, Alan J. Stewart, Petra Popovics   +9 more
core   +1 more source

Expression of mRNA for phospholipase A(2), cyclooxygenases, and lipoxygenases in cultured human umbilical vascular endothelial and smooth muscle cells and in biopsies from umbilical arteries and veins [PDF]

, 1998
Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX).
Söderkvist, Peter, Gidlöf, Anders, Uhl, Eberhard, Carlsson, Maria, Öst, Martin, Sirsjö, Allan   +5 more
core   +1 more source

Stimulated platelets release equivalent amounts of arachidonate from phosphatidylcholine, phosphatidylethanolamine, and inositides.

Journal of Lipid Research, 1988
Thrombin-induced changes in arachidonate content of platelet phospholipids were quantitated to establish the ultimate origins of this eicosanoid precursor.
M J Broekman
doaj   +1 more source

In Silico Analysis of Honeybee Venom Protein Interaction with Wild Type and Mutant (A82V + P375S) Ebola Virus Spike Protein

Biologics, 2022
Venom from different organisms was used in ancient times to treat a wide range of diseases, and to combat a variety of enveloped and non-enveloped viruses.
Muhammad Muzammal, Muzammil Ahmad Khan, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Maitham A. Al Hawaj, Arshad Farid   +5 more
doaj   +1 more source

Phospholipase A Activates Hemostasis

Drug Target Insights, 2007
Background Phospholipases A 2 (PLA 2 ) are aggressive enzymes that can destroy phospholipids of cell membranes. The resulting cell fragments trigger the kallikrein—mediated contact phase of coagulation. The aim of the present study was to expose citrated
Thomas W. Stief M.D.
doaj   +1 more source

Phospholipases and the network of auxin signal transduction with ABP1 and TIR1 as two receptors: a comprehensive and provocative model

Frontiers in Plant Science, 2012
Phospholipase D (PLD), secreted phospholipase A2 (sPLA2) and patatin-related phospholipase A (pPLA) are important elements in auxin signal transduction. PLDζ2 has a function in auxin transport.
Günther F. E. Scherer, Corinna eLabusch, Yunus eEffendi   +2 more
doaj   +1 more source

Subcellular localization of the phospholipases A of rat heart: evidence for a cytosolic phospholipase A1.

Journal of Lipid Research, 1985
During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process.
G Nalbone, K Y Hostetler
doaj   +1 more source

Predicting the mechanism of phospholipidosis [PDF]

, 2012
The mechanism of phospholipidosis is still not well understood. Numerous different mechanisms have been proposed, varying from direct inhibition of the breakdown of phospholipids to the binding of a drug compound to the phospholipid, preventing breakdown.
Mitchell, JBO, Glen, RC, Glen Robert C, Nigsch Florian, Mussa, HY, Robert Lowe, Florian Nigsch, Robert C Glen, Nigsch, F, Mussa, Hamse Y., Lowe, R, Glen, Robert C., Lowe Robert, John BO Mitchell, Mitchell John BO, Nigsch, Florian, Lowe, Robert, Mussa Hamse Y, Hamse Y Mussa, Mitchell, John B. O.   +19 more
core   +5 more sources

Lipid vesicle fusion induced by phospholipase C activity in model bile.

Journal of Lipid Research, 1993
Using a system of phosphatidylcholine-cholesterol vesicles to model the vesicle phase of mammalian bile (1:1 molar ratio) we evaluated whether very small amounts of C.
TE Little, H Madani, SP Lee, EW Kaler
doaj   +1 more source

Phospholipases A1 [PDF]

, 2011
Research in the author's laboratory is supported in part by a Wellcome Trust Senior Research Fellowship (067441), and Wellcome Trust project grants (086658 and 093228) and a Wellcome Trust Prize Studentship (G.S.R).Phospholipase A1 (PLA1) is an enzyme ...
Smith, Terry K., Gregory S. Richmond, Terry K. Smith, Richmond, Gregory S.   +3 more
core   +1 more source