Results 51 to 60 of about 2,559,320 (125)
Nature Communications, 2021 Phospholipase ExoU from Pseudomonas aeruginosa acts on plasma membrane lipids in infected cells, causing membrane rupture and host cell necrosis. Here, Deruelle et al.
Vincent Deruelle +6 more
doaj +1 more source
Mapping Complex Networks: Exploring Boolean Modeling of Signal Transduction Pathways [PDF]
arXiv, 2009 In this study, we explored the utility of a descriptive and predictive bionetwork model for phospholipase C-coupled calcium signaling pathways, built with non-kinetic experimental information. Boolean models generated from these data yield oscillatory activity patterns for both the endoplasmic reticulum resident inositol-1,4,5-trisphosphate receptor ...
arxiv
Regulation of phospholipase D [PDF]
FEBS Letters, 1999 Structural studies of plant and bacterial members of the phospholipase D (PLD) superfamily are providing information about the role of the conserved HKD domains in the structure of the catalytic center and the catalytic mechanism of mammalian PLD isozymes (PLD1 and PLD2).
openaire +4 more sources
Phospholipase A2 Biochemistry [PDF]
Cardiovascular Drugs and Therapy, 2008 The phospholipase A(2) (PLA(2)) superfamily consists of many different groups of enzymes that catalyze the hydrolysis of the sn-2 ester bond in a variety of different phospholipids. The products of this reaction, a free fatty acid, and lysophospholipid have many different important physiological roles.
Burke, John E, Dennis, Edward A
openaire +4 more sources
A Piece of the Lepton Theory from a Probability [PDF]
arXiv, 2001 A masses of a leptons deduced from a representation of a probability density vector by a spinors. A massive W and Z bosons and a massless A boson are obtained from a transformations for which a density vector is invariant.
arxiv
On a question of A. Balog [PDF]
arXiv, 2015 We give a partial answer to a conjecture of A. Balog, concerning the size of AA+A, where A is a finite subset of real numbers. Also, we prove several new results on the cardinality of A:A+A, AA+AA and A:A + A:A.
arxiv
Mammalian Phospholipase A2: Phospholipase A2 Receptor
Biological and Pharmaceutical Bulletin, 2004 The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family such as the mannose receptor. PLA2R regulates a variety of biological responses elicited by secretory phospholipase A2s (sPLA2s). Group IB sPLA2 acts as an endogenous ligand to induce cell proliferation and lipid mediator production ...
openaire +4 more sources
PLoS ONE, 2014 BackgroundThe aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A2 inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A2 activity.MethodsPatients ...
Joel L Johnson +7 more
doaj +1 more source
Enumeration of symmetric centered rhombus tilings of a hexagon [PDF]
arXiv, 2013 A rhombus tiling of a hexagon is said to be centered if it contains the central lozenge. We compute the number of vertically symmetric rhombus tilings of a hexagon with side lengths $a, b, a, a, b, a$ which are centered. When $a$ is odd and $b$ is even, this shows that the probability that a random vertically symmetric rhombus tiling of a $a, b, a, a ...
arxiv
The substrate specificity of phospholipase A
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1963 Investigations on variously modified analogues of phospholipids elucidated the following substrate characteristics for phospholipase A (Crotalus adamanteus). 1. 1. Within the class of α-phosphoglycerides l-isomers are readily hydrolysed, while d-α-phospholipids appeared not to be attacked. 2. 2.
Deenen, L.L.M. van, Haas, Gerard H. de
openaire +3 more sources