Results 1 to 10 of about 59,281 (286)
Sucrose Treatment Enhances the Electrotransfer of DNA by Activating Phospholipase A2 [PDF]
PharmaceuticsOur previous study discovered that sucrose and other non-reducing sugars (e.g., trehalose and raffinose) could be used to improve the electrotransfer (ET) of molecular cargo, including DNA, mRNA, and ribonucleoprotein in various cell lines and primary ...
Chunxi Wang +3 more
doaj +2 more sources
Isolation, Characterization, and Biological Activity of Phospholipase A2 (PLA2) and Hyaluronidase from Iranian Honey Bee Venom (Apis Mellifera meda) [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 ObjectiveBee venom contains various enzymes such as hyaluronidase and phospholipase A2, which have medical and pharmaceutical applications. In several studies, the activity of phospholipase A2 and hyaluronidase has been reported in different bee species,
Mahmood Nazari +2 more
doaj +1 more source
Biologics, 2022 Venom from different organisms was used in ancient times to treat a wide range of diseases, and to combat a variety of enveloped and non-enveloped viruses.
Muhammad Muzammal +5 more
doaj +1 more source
Identification and characterization of the first endogenous phospholipase A2 inhibitor from a non-venomous tropical snake, Boa constrictor (Serpentes: Boidae) [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Endogenous phospholipase A2 inhibitors from snake blood (sbPLIs) have been isolated from several species around the world, with the primary function of self-protection against the action of toxic phospholipases A2. In American snakes, sbPLIs
Consuelo L. Fortes-Dias +4 more
doaj +1 more source
Phospholipase A2 Biochemistry [PDF]
Cardiovascular Drugs and Therapy, 2008 The phospholipase A(2) (PLA(2)) superfamily consists of many different groups of enzymes that catalyze the hydrolysis of the sn-2 ester bond in a variety of different phospholipids. The products of this reaction, a free fatty acid, and lysophospholipid have many different important physiological roles.
Burke, John E, Dennis, Edward A
openaire +4 more sources
Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells. [PDF]
PLoS ONE, 2013 Secretory phospholipase A2 (sPLA2) is a critical component of insect and snake venoms and is secreted by mammalian leukocytes during inflammation. Elevated secretory PLA2 concentrations are associated with autoimmune diseases and septic shock. Many sPLA2'
Steffen Nyegaard +3 more
doaj +1 more source
Secretory Phospholipase A2 [PDF]
Biological and Pharmaceutical Bulletin, 2004 Secretory phospholipase A2 (sPLA2) is a growing family of structurally related, disulfide-rich, low molecular weight, lipolytic enzymes with a His-Asp catalytic dyad. sPLA2s are distributed in a wide variety of vertebrate and invertebrate animals, plants, bacteria, and viruses, and there are 10 catalytically active sPLA2 isozymes in mammals.
Makoto Murakami, Ichiro Kudo
openaire +3 more sources
Toxics, 2023 In recent years, intensive studies have been carried out on the management of agricultural insect pests using botanical insecticides in order to decrease the associated environmental hazards. Many studies have tested and characterized the toxic action of
Mariappan Madasamy +6 more
doaj +1 more source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022 Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the
L. V. Galebskaya +3 more
doaj +1 more source
Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs).
Roberta Tancredi Francesco dos Santos +7 more
doaj +1 more source