Results 1 to 10 of about 213,670 (146)

Phospholipase A2 isolated from the venom of Crotalus durissus terrificus inactivates dengue virus and other enveloped viruses by disrupting the viral envelope. [PDF]

open access: yesPLoS ONE, 2014
The Flaviviridae family includes several virus pathogens associated with human diseases worldwide. Within this family, Dengue virus is the most serious threat to public health, especially in tropical and sub-tropical regions of the world.
Vanessa Danielle Muller   +8 more
doaj   +2 more sources

Antimicrobial activity of apitoxin, melittin and phospholipase A2 of honey bee (Apis mellifera) venom against oral pathogens

open access: yesAnais da Academia Brasileira de Ciências, 2015
In this work, we used the Minimum Inhibitory Concentration (MIC) technique to evaluate the antibacterial potential of the apitoxin produced by Apis mellifera bees against the causative agents of tooth decay.
Luís F. Leandro   +6 more
doaj   +2 more sources

Isolation, Characterization, and Biological Activity of Phospholipase A2 (PLA2) and Hyaluronidase from Iranian Honey Bee Venom (Apis Mellifera meda) [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2023
ObjectiveBee venom contains various enzymes such as hyaluronidase and phospholipase A2, which have medical and pharmaceutical applications. In several studies, the activity of phospholipase A2 and hyaluronidase has been reported in different bee species,
Mahmood Nazari   +2 more
doaj   +1 more source

The Phospholipase A2 Superfamily: Structure, Isozymes, Catalysis, Physiologic and Pathologic Roles

open access: yesInternational Journal of Molecular Sciences, 2023
The phospholipase A2 (PLA2) superfamily of phospholipase enzymes hydrolyzes the ester bond at the sn-2 position of the phospholipids, generating a free fatty acid and a lysophospholipid.
Shibbir Ahmed Khan, M. Ilies
semanticscholar   +1 more source

In Silico Analysis of Honeybee Venom Protein Interaction with Wild Type and Mutant (A82V + P375S) Ebola Virus Spike Protein

open access: yesBiologics, 2022
Venom from different organisms was used in ancient times to treat a wide range of diseases, and to combat a variety of enveloped and non-enveloped viruses.
Muhammad Muzammal   +5 more
doaj   +1 more source

Identification and characterization of the first endogenous phospholipase A2 inhibitor from a non-venomous tropical snake, Boa constrictor (Serpentes: Boidae) [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: Endogenous phospholipase A2 inhibitors from snake blood (sbPLIs) have been isolated from several species around the world, with the primary function of self-protection against the action of toxic phospholipases A2. In American snakes, sbPLIs
Consuelo L. Fortes-Dias   +4 more
doaj   +1 more source

Updating Phospholipase A2 Biology

open access: yesBiomolecules, 2020
The phospholipase A2 (PLA2) superfamily contains more than 50 enzymes in mammals that are subdivided into several distinct families on a structural and biochemical basis.
M. Murakami, Hiroyasu Sato, Y. Taketomi
semanticscholar   +1 more source

Phospholipase A2

open access: yesDefinitions, 2020
Phospholipase A2 (148 aa, ~16 kDa) is encoded by the human PLA2G1B gene. This protein plays a role in fatty acid metabolism.

semanticscholar   +1 more source

Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells. [PDF]

open access: yesPLoS ONE, 2013
Secretory phospholipase A2 (sPLA2) is a critical component of insect and snake venoms and is secreted by mammalian leukocytes during inflammation. Elevated secretory PLA2 concentrations are associated with autoimmune diseases and septic shock. Many sPLA2'
Steffen Nyegaard   +3 more
doaj   +1 more source

Insecticidal Mechanism of Botanical Crude Extracts and Their Silver Nanoliquids on Phenacoccus solenopsis

open access: yesToxics, 2023
In recent years, intensive studies have been carried out on the management of agricultural insect pests using botanical insecticides in order to decrease the associated environmental hazards. Many studies have tested and characterized the toxic action of
Mariappan Madasamy   +6 more
doaj   +1 more source

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