Results 31 to 40 of about 67,252 (282)

Dietary Fish Oil and Zinc Reduced Plasma Prostaglandin E2 Content by Inhibiting Phospholipase A2 Production in Broilers

open access: yesThe Journal of Poultry Science, 2014
Two-factor experiment was designed to examine from lipid metabolism, proinflammatory eicosanoids, and lipid peroxidation for investigating the effects of dietary oils and zinc levels of cardiovascular system of broilers.
Guanzhong Liu   +6 more
doaj   +1 more source

Phospholipase A2 as a mechanosensor

open access: yesBiophysical Journal, 1995
Osmotic swelling of large unilamellar vesicles (LUVs) causes membrane stretching and thus reduces the lateral packing of lipids. This is demonstrated to modulate strongly the catalytic activity of phospholipase A2 (PLA2) toward a fluorescent phospholipid, 1-palmitoyl-2-[(6-pyren-1-yl)]decanoyl-sn-glycero-3-phosphocholine (PPDPC) residing in LUVs ...
Lehtonen, J.Y., Kinnunen, P.K.
openaire   +2 more sources

Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial.

open access: yesPLoS ONE, 2014
BackgroundThe aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A2 inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A2 activity.MethodsPatients ...
Joel L Johnson   +7 more
doaj   +1 more source

Stimulated platelets release equivalent amounts of arachidonate from phosphatidylcholine, phosphatidylethanolamine, and inositides.

open access: yesJournal of Lipid Research, 1988
Thrombin-induced changes in arachidonate content of platelet phospholipids were quantitated to establish the ultimate origins of this eicosanoid precursor.
M J Broekman
doaj   +1 more source

Phospholipase A2 and inflammation

open access: yesMolecular Medicine Today, 1995
Increased expression of secreted group II phospholipase A 2 (sPLA2) is associated with inflammation 1.This enzyme can promote a variety of potentially harmful events, which have been attributed to its catalytic activity. However, the possibility that sPLA 2 may also exert actions that do not depend on its catalytic activity has generally not been ...
Lomonte, Bruno   +2 more
openaire   +4 more sources

Synthesis of photoreactive phosphatidylethanolamine and its interaction with phospholipase A2.

open access: yesJournal of Lipid Research, 1994
A photoreactive derivative of phosphatidylethanolamine, N-(4-azidobenzoyl)phosphatidylethanolamine (AB-PE), was synthesized by acylation of phosphatidylethanolamine with an N-hydroxysuccinimide ester of 4-azidobenzoic acid.
R Rajasekharan, J D Kemp
doaj   +1 more source

Generation of feeder-independent transgene-free iPSC lines from a young-onset Parkinson’s disease (YOPD) patient with a homozygous PLA2G6: c.2222G>A (p. Arg741Gln) mutation (NCBSi003-A) and unaffected heterozygous parent (NCBSi004-A)

open access: yesStem Cell Research, 2023
Phospholipase A2 group 6 (PLA2G6, iPLA2β or PARK14) gene encodes a calcium-independent group 6 phospholipase A2 enzyme and is associated with young-onset autosomal recessive Parkinson’s disease (PD). We generated human induced pluripotent stem cell (iPSC)
Renjitha Gopurappilly   +4 more
doaj   +1 more source

Mammalian Phospholipase A2: Phospholipase A2 Receptor

open access: yesBiological and Pharmaceutical Bulletin, 2004
The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family such as the mannose receptor. PLA2R regulates a variety of biological responses elicited by secretory phospholipase A2s (sPLA2s). Group IB sPLA2 acts as an endogenous ligand to induce cell proliferation and lipid mediator production ...
openaire   +3 more sources

Clofazimine Induced Suicidal Death of Human Erythrocytes

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: The antimycobacterial riminophenazine clofazimine has previously been shown to up-regulate cellular phospholipase A2 and to induce apoptosis.
Arbace Officioso   +3 more
doaj   +1 more source

Effect of phospholipids on the structure of Triatoma infestans lipophorin studied by fluorescence methods

open access: yesJournal of Lipid Research, 1996
To study the role of phospholipids in the lipophorin structure, they were removed by phospholipase A2 treatment. Fluorescence lifetimes and accessibility to acrylamide quenching of different diphenylhexatrienyl derivatives, which were used as analogues ...
O J Rimoldi, H A Garda, R R Brenner
doaj   +1 more source

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