Results 91 to 100 of about 321,900 (228)

Mechanism(s) of activation of secretory phospholipase A2s in mouse keratinocytes

open access: yesJournal of Lipid Research, 1999
The differential activation of different members of the phospholipase A2 (PLA2) superfamily and their regulation are important as one or more of them regulates the production of eicosanoids and others may contribute to the formation of other lipid ...
Bangyan Li-Stiles, Susan M. Fischer
doaj   +1 more source

Cancer therapy-induced PAFR ligand expression: any role for caspase activity? [PDF]

open access: yes, 2017
No abstract ...
G Ichim   +7 more
core   +1 more source

Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2

open access: yesJournal of Lipid Research, 2012
Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a unique member of the phospholipase A2 superfamily.
R. Rosenson, D. Stafforini
semanticscholar   +1 more source

Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation

open access: yesJournal of Lipid Research, 2010
Neuroinflammation, caused by 6 days of intracerebroventricular infusion of a low dose of lipopolysaccharide (LPS; 0.5 ng/h), stimulates brain arachidonic acid (AA) metabolism in rats, but 6 weeks of lithium pretreatment reduces this effect.
Mireille Basselin   +6 more
doaj   +1 more source

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia [PDF]

open access: yes, 2014
© The Author 2014. Published by Oxford University Press This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution,
Al-Mahdawi   +57 more
core   +2 more sources

Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis

open access: yesJournal of Lipid Research, 2008
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff   +2 more
doaj   +1 more source

Positional specificity of lysosomal phospholipase A2

open access: yesJournal of Lipid Research, 2006
Lysosomal phospholipase A2 (Lpla2) is highly expressed in alveolar macrophages and may mediate the phospholipid metabolism of surfactant. Studies on the properties of this phospholipase are consistent with the presence of both phospholipase A1 and ...
Akira Abe   +2 more
doaj   +1 more source

Physics-based visual characterization of molecular interaction forces [PDF]

open access: yes, 2017
Molecular simulations are used in many areas of biotechnology, such as drug design and enzyme engineering. Despite the development of automatic computational protocols, analysis of molecular interactions is still a major aspect where human comprehension ...
Estrada, Jorge   +5 more
core   +4 more sources

Secreted phospholipase A2 and mast cells

open access: yesAllergology International, 2015
Phospholipase A2s (PLA2s) are a group of enzymes that hydrolyze the sn-2 position of phospholipids to release (typically unsaturated) fatty acids and lysophospholipids, which serve as precursors for a variety of bioactive lipid mediators.
Makoto Murakami, Yoshitaka Taketomi
doaj   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

open access: yes, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core  

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