Results 111 to 120 of about 56,037 (217)

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki, Mercè Pallàs, Carmen Escolano   +2 more
wiley   +1 more source

Secreted phospholipase A2 group X regulates peripheral sensitization to allergen. [PDF]

JCI Insight
Murphy RC, Lai Y, Chow YH, Liu M, Hondowicz BD, An D, Pepper M, Altemeier WA, Hallstrand TS.   +8 more
europepmc   +1 more source

Evolution of Phospholipase A2 in Bees and Flies. [PDF]

Ecol Evol
Yang S, Wu M, Feng P.
europepmc   +1 more source

Loss of calcium-dependent phospholipase A2 contributes to multi-omic changes in mouse denervated skeletal muscle. [PDF]

Physiol Rep
Czyżowska-Froemling A, Xu H, Harold K, Thomason J, Kneuper K, Duggan E, Pranay A, Zhu J, Agbaga MP, Georgescu C, Tyrrell V, O'Donnell V, Humphries K, Van Remmen H, Brown JL.   +14 more
europepmc   +1 more source

Phospholipase A2 Isoforms in Lung Immunity and Respiratory Infections: Potential Targets for Next-Generation Therapy. [PDF]

Int J Mol Sci
Joshi S, Walter K, Hamiel D, Saxena D, Zheng J.   +4 more
europepmc   +1 more source

Obinutuzumab Treatment in Rituximab- and Bortezomib-Resistant Phospholipase A2 Receptor Antibody-Positive Membranous Nephropathy. [PDF]

Cureus
Yildirim U, Ozkurt S, Yalcin AU.
europepmc   +1 more source

Endogenous "Time Bomb" - Mislocalized Phospholipase A2 as a Critical Mediator of Ultra-Rapid Mortality in Sepsis and Acute Lung Injury. [PDF]

Adv Sci (Weinh)
Wang J, Xu Z, Wang L, Sui X, Luo Y, Zhao X, Yang J, Wang Y.   +7 more
europepmc   +1 more source

Anti-phospholipase A2 Receptor Membranous Nephropathy Presenting as Common Geriatric Complaints: A Case Report. [PDF]

Cureus
Li WTV, Wu KH, Lin OY.
europepmc   +1 more source

Lipoprotein-associated phospholipase A2 and complications of diabetes mellitus: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Guo S, Zhao X.
europepmc   +1 more source