Results 91 to 100 of about 315,246 (280)
Lipoprotein-associated phospholipase A2 and venous thromboembolism: A prospective study [PDF]
, 2013 Plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) is an inflammatory marker associated positively with atherothrombotic risk.
Roetker, Nicholas S. +6 more
core +1 more source
Phytotherapy Research, EarlyView.Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen +10 more
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2015 In this work, we used the Minimum Inhibitory Concentration (MIC) technique to evaluate the antibacterial potential of the apitoxin produced by Apis mellifera bees against the causative agents of tooth decay.
Luís F. Leandro +6 more
doaj +1 more source
Glucocorticoid receptor stabilization: Relative effects of molybdate ion on inactivation by alkaline phosphatase and phospholipase A2 [PDF]
, 1983 Glucocorticoid receptors in cytosol preparations from rat liver or mouse L cells are inactivated by phospholipase A2 or calf intestine alkaline phosphatase. Molybdate ion, an inhibitor of a variety of phosphatase enzymes, does not prevent inactivation of
Pratt, William B. +2 more
core +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
Mechanism(s) of activation of secretory phospholipase A2s in mouse keratinocytes
Journal of Lipid Research, 1999 The differential activation of different members of the phospholipase A2 (PLA2) superfamily and their regulation are important as one or more of them regulates the production of eicosanoids and others may contribute to the formation of other lipid ...
Bangyan Li-Stiles, Susan M. Fischer
doaj +1 more source
The Localization and Partial Characterization of Rat Testicular Phospholipase A2
, 1977 Preparations of mature rat testes were assayed for phospholipase A2 activity. Two separate phospholipase A2 enzymes were observed with two pH optima: one at pH 3.5 and the second at pH 7.5-8.0.
Boccio, James R.
core
Environmental Toxicology, EarlyView.ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane +8 more
wiley +1 more source
Positional specificity of lysosomal phospholipase A2
Journal of Lipid Research, 2006 Lysosomal phospholipase A2 (Lpla2) is highly expressed in alveolar macrophages and may mediate the phospholipid metabolism of surfactant. Studies on the properties of this phospholipase are consistent with the presence of both phospholipase A1 and ...
Akira Abe +2 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source