Results 121 to 130 of about 255,660 (330)
Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as Neural Signaling Molecules [PDF]
, 2008 The definitive version is available at www3.interscience.wiley ...
Cravatt, BF +3 more
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Advanced Science, EarlyView.This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta +14 more
wiley +1 more source
Journal of Pharmacological Sciences, 2003 The intracellular signalling pathway for a-adrenoceptor-mediated negative inotropy was studied pharmacologically in isolated adult mouse ventricle. The negative inotropy was inhibited by GF-109203X, a nonselective protein kinase C inhibitor.
Kazuhide Nishimaru +3 more
doaj +1 more source
The Deletion of 14 Amino Acids in the Seventh Transmembrane Domain of a Naturally Occurring Calcitonin Receptor Isoform Alters Ligand Binding and Selectively Abolishes Coupling to Phospholipase C [PDF]
, 1996 Jia‐Fwu Shyu +3 more
openalex +1 more source
Advanced Science, EarlyView.Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen +9 more
wiley +1 more source
Biotechnology & Biotechnological Equipment, 1997 ABSTRACTPhospholipases C are defined as enzymes that catalyze the hydrolysis of phospholipids into 1,2-diacylglycerols (or N-acylsphingosine in the case of sphingomyelin) and phosphate monoester. Some of the phospholipaes C act best towards phosphatidylcholine (sometimes referred to as PC-specific phospholipase C) and show some activity towards other ...
openaire +1 more source
Isolation of cDNA encoding the catalytic site of phosphatidylinositol-specific phospholipase C fromCoffea arabicaL. [PDF]
, 2008 Lucila A. Sánchez-Cach +6 more
openalex +1 more source
The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells [PDF]
, 1992 Thyrotropin-releasing hormone stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) in GH3 cell membranes. The stimulation of the phosphoinositide phospholipase C (PI/PLC) activity can be blocked by incubation of GH3 membranes with ...
Aragay, Anna M. +2 more
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Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
On the interactions of lipids and proteins in the red blood cell membrane [PDF]
, 1970 The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements.
Chan, Sunney I. +4 more
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