Results 81 to 90 of about 28,776 (298)
Myocardial phospholipases A2 and oxidative stress [PDF]
, 2012 Heart and vascular diseases, in which oxidative stress plays an important role, are the most frequent cause of death in developed countries. Therefore today's researches focus on clarifying signaling pathway and their components that operates in these ...
Závišková, Kristýna
core
Advanced Science, EarlyView.Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu +7 more
wiley +1 more source
Acta Médica Costarricense, 2009 Justificación y objetivos: Los pacientes internados en hospitales, principalmente aquellos que se encuentran severamente enfermos, son más susceptibles a las infecciones por hongos oportunistas, en comparación con la población general.
Pedro Carrillo-Dover +3 more
doaj
Phospholipase D and phosphatidic acid in the biogenesis and cargo loading of extracellular vesicles
Journal of Lipid Research, 2018 Extracellular vesicles released by viable cells (exosomes and microvesicles) have emerged as important organelles supporting cell-cell communication.
Antonio Luis Egea-Jimenez +1 more
doaj +1 more source
Advanced Science, EarlyView.An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan +7 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Some new 3H-quinazolin-4-one derivatives were synthesised and screened for anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities.
Nahed N. E. El-Sayed +6 more
doaj +1 more source
Study of phospholipases in Trypanosoma brucei brucei
, 2021 La trypanosomiase africaine est une parasitose vectorielle qui touche bon nombre de mammifères en Afrique. Parmi eux, nous pouvons compter les Hommes et les bêtes d’élevage. L’un des symptômes de cette pathologie chez l’animal est l’anémie. On ne connaît
Monic, Sarah
core
Advanced Science, EarlyView.Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha +5 more
wiley +1 more source
Intraspecific Variation of Centruroides Edwardsii Venom from Two Regions of Colombia
Toxins, 2014 We report the first description studies, partial characterization, and intraspecific difference of Centruroides edwardsii, Gervais 1843, venom. C. edwardsii from two Colombian regions (Antioquia and Tolima) were evaluated.
Sebastián Estrada-Gómez +3 more
doaj +1 more source
Identification of Two Secreted Phospholipases A2 in Human Epidermis [PDF]
, 2000 Phospholipases A2 are enzymes that catalyze the release of fatty acids from the sn-2 position of phospholipids. Fatty acids have been suggested to play a key role in the barrier function of the epidermis.
Tarroux, Roger +7 more
core +1 more source