Results 1 to 10 of about 2,596,999 (237)
Phospholipases A and Lysophospholipases in protozoan parasites. [PDF]
Microb Cell, 2023 Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of the immune ...
Hervé P +3 more
europepmc +2 more sources
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms.
Vavilovskii Zhurnal Genet SelektsiiThe phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
Bocharnikova ME +2 more
europepmc +2 more sources
Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells. [PDF]
Transl OncolTriple-negative breast cancer (TNBC) is the most lethal breast cancer subtype, leading to poor patient outcomes despite aggressive treatment with surgery, radiation, and chemotherapy. There are currently no clinical tests available which measure early on
Tressler CM +5 more
europepmc +2 more sources
Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants
Frontiers in Plant Science, 2019 Phospholipases (PLs) are lipid-hydrolyzing enzymes known to have diverse signaling roles during plant abiotic and biotic stress responses. They catalyze lipid remodeling, which is required to generate rapid responses of plants to environmental cues ...
Tomáš Tak +2 more
exaly +3 more sources
Journal of Lipid Research, 1964 Egg phosphatidyl ethanolamine is degraded to lysophosphatidyl ethanolamine and fatty acids by a phospholipase in post-heparin plasma at rates of 10 to 30 μmoles/hr per ml plasma. The optimal system for measuring this enzyme contained albumin and (NH4)2SO4, and the optimal pH was 8.8–9.1.
William Vogel, Leslie Zieve
openalex +5 more sources
Phospholipid Signaling in Crop Plants: A Field to Explore. [PDF]
Plants (Basel)In plant models such as Arabidopsis thaliana, phosphatidic acid (PA), a key molecule of lipid signaling, was shown not only to be involved in stress responses, but also in plant development and nutrition.
Amokrane L +6 more
europepmc +2 more sources
F1000Research, 2021 Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani +4 more
doaj +1 more source
Phospholipases in Gliomas: Current Knowledge and Future Perspectives from Bench to Bedside
Biomolecules, 2023 Phospholipases are essential intermediaries that work as hydrolyzing enzymes of phospholipids (PLs), which represent the most abundant species contributing to the biological membranes of nervous cells of the healthy human brain.
Maria Vittoria Marvi +15 more
doaj +1 more source
Phospholipases A in Trypanosomatids [PDF]
Enzyme Research, 2011 Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A1, A2, C, and D. Phospholipases A1and A2activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell ...
María Laura Belaunzarán +2 more
openaire +4 more sources
Human phospholipases A2: a functional and evolutionary analysis
Вавиловский журнал генетики и селекции, 2023 Phospholipases A2 (PLA2) are capable of hydrolyzing the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids. The PLA2 superfamily enzymes are widespread and present in most mammalian cells and tissues, regulating metabolism,
I. I. Turnaev +2 more
doaj +1 more source