Results 21 to 30 of about 2,596,999 (237)

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

open access: yesToxins, 2021
A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments.
José María Gutiérrez   +6 more
doaj   +1 more source

Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2.

open access: yesPLoS ONE, 2014
Phospholipases A2 represent the most abundant family of snake venom proteins. They manifest an array of biological activities, which is constantly expanding. We have recently shown that a protein bitanarin, isolated from the venom of the puff adder Bitis
Catherine A Vulfius   +9 more
doaj   +1 more source

Stalling autophagy: a new function for Listeria phospholipases

open access: yesMicrobial Cell, 2014
Listeria monocytogenes is a Gram-positive bacterial pathogen that induces its own uptake in non-phagocytic cells. Following invasion, Listeria escapes from the entry vacuole through the secretion of a pore-forming toxin, listeriolysin O (LLO) that acts ...
Ivan Tattoli   +3 more
doaj   +1 more source

Modification of lecithin-based emulsions with phospholipases

open access: yesCyTA - Journal of Food, 2020
Phospholipases have been used in different food processes, but mainly on degumming vegetable oils. More recently, the use of these enzymes has been extended to the manufacture of bread and dairy products. However, little is known on phospholipases effect
Dely Rubí Chávez-Garay   +6 more
doaj   +1 more source

Possible Involvement of Intracellular Calcium-Independent Phospholipase A2 in the Release of Secretory Phospholipases from Mast Cells—Increased Expression in Ileal Mast Cells of Crohn’s Disease

open access: yesCells, 2019
Increased activity of secretory phospholipases A2 (sPLA2) type-II was previously observed in ileum of Crohn’s disease (CD). Our aims were to explore the involvement of calcium-independent (i)PLA2β in the release of sPLA2s from the human mast ...
Ulrika Christerson   +4 more
doaj   +1 more source

Inflammatory Effects of Bothrops Phospholipases A2: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation

open access: yesToxins, 2021
Phospholipases A2s (PLA2s) constitute one of the major protein groups present in the venoms of viperid and crotalid snakes. Snake venom PLA2s (svPLA2s) exhibit a remarkable functional diversity, as they have been described to induce a myriad of toxic ...
Vanessa Moreira   +5 more
doaj   +1 more source

Shapes and Positions of Black Hole Shadows in Accretion Disks and Spin Parameters of Black Holes [PDF]

open access: yesJ.Korean Phys.Soc.45:S1808-S1812,2004; Astrophys.J.611:996-1004,2004, 2004
Can we determine a spin parameter of a black hole by observation of a black hole shadow in an accretion disk? In order to answer this question, we make a qualitative analysis and a quantitative analysis of a shape and a position of a black hole shadow casted by a rotating black hole on an optically thick accretion disk and its dependence on an angular ...
arxiv   +1 more source

Enzymatic Degumming of Rice Bran Oil Using Different Commercial Phospholipases and Their Cocktails

open access: yesLife, 2021
Rice bran oil is a highly nutritious vegetable oil, as it is rich in tocols and γ-oryzanol. Degumming is the first step in the vegetable oil refining process, and its main objective is the removal of phospholipids or gums. In the present study, enzymatic
Mayara S. Rodrigues   +7 more
doaj   +1 more source

Phospholipases A1 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2011
Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire   +2 more sources

Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper

open access: yesBiomedicines, 2020
Feae’s viper Azemipos feae belongs to the Azemiopinae subfamily of the Viperidae family. The effects of Viperidae venoms are mostly coagulopathic with limited neurotoxicity manifested by phospholipases A2. From A.
Vladislav V. Babenko   +10 more
doaj   +1 more source

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