Results 21 to 30 of about 72,860 (341)
Interface of Phospholipase Activity, Immune Cell Function, and Atherosclerosis
Biomolecules, 2020 Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane ...
Robert M. Schilke +3 more
doaj +1 more source
Signal-activated phospholipase regulation of leukocyte chemotaxis
Journal of Lipid Research, 2009 Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj +1 more source
mBio, 2023 For its replication within red blood cells, the malaria parasite depends on a highly active and regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as phospholipases are, therefore, potential drug targets.
Paul-Christian Burda +12 more
doaj +1 more source
Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]
, 2019 Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron +2 more
core +6 more sources
Lipases and proteases inhibition by Averrhoa carambola L. fruit extracts
Phytomedicine Plus, 2021 Background: Proteases and phospholipases A2 are involved in processes related to hemostasis. Medicinal plants which contain bioactive phytochemicals, can act as enzymatic modulators.
Daniela Aparecida Oliveira +4 more
doaj +1 more source
Journal of Lipid Research, 1985 During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process.
G Nalbone, K Y Hostetler
doaj +1 more source
A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis. [PDF]
PLoS ONE, 2012 BACKGROUND: Presynaptically neurotoxic phospholipases A(2) inhibit synaptic vesicle recycling through endocytosis. PRINCIPAL FINDINGS: Here we provide insight into the action of a presynaptically neurotoxic phospholipase A(2) ammodytoxin A (AtxA) on ...
Mojca Mattiazzi +9 more
doaj +1 more source
Approaches to the study of mammalian cellular phospholipases.
Journal of Lipid Research, 1985 The purpose of this article is to present some problems encountered in the study of cellular phospholipases and some approaches used in answering these problems.
M Waite
doaj +1 more source
An amphitropic cAMP-binding protein in yeast mitochondria [PDF]
, 1989 : We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W. +43 more
core +3 more sources
Group XV phospholipase A2, a lysosomal phospholipase A2 [PDF]
Progress in Lipid Research, 2011 A phospholipase A₂ was identified from MDCK cell homogenates with broad specificity toward glycerophospholipids including phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and phosphatidylglycerol. The phospholipase has the unique ability to transacylate short chain ceramides.
James A. Shayman +4 more
openaire +1 more source