Results 21 to 30 of about 22,290,738 (402)

Approaches to the study of mammalian cellular phospholipases.

Journal of Lipid Research, 1985
The purpose of this article is to present some problems encountered in the study of cellular phospholipases and some approaches used in answering these problems.
M Waite
doaj   +1 more source

Group XV phospholipase A2, a lysosomal phospholipase A2 [PDF]

Progress in Lipid Research, 2011
A phospholipase A₂ was identified from MDCK cell homogenates with broad specificity toward glycerophospholipids including phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and phosphatidylglycerol. The phospholipase has the unique ability to transacylate short chain ceramides.
James A. Shayman, Robert Kelly, Jessica Kollmeyer, Yongqun He, Akira Abe   +4 more
openaire   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources

A novel lipase with dual localisation in Trypanosoma brucei

Scientific Reports, 2022
Phospholipases are esterases involved in lipid catabolism. In pathogenic micro-organisms (bacteria, fungi, parasites) they often play a critical role in virulence and pathogenicity. A few phospholipases (PL) have been characterised so far at the gene and
S.G. Monic, A. Lamy, M. Thonnus, T. Bizarra-Rebelo, F. Bringaud, T. K. Smith, L. M. Figueiredo, L. Rivière   +7 more
doaj   +1 more source

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. [PDF]

, 2017
Cytosolic phospholipase A2 (GIVA cPLA2) is the only PLA2 that exhibits a marked preference for hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid and lysophospholipids and giving rise to the generation of ...
Barbayianni, Efrosini, Dennis, Edward A, Galiatsatou, Gerasimia, Kokotos, George, Kokotou, Maroula G, Koutoulogenis, Giorgos, Limnios, Dimitris, Magrioti, Victoria, Mouchlis, Varnavas D, Navratil, Aaron, Satpathy, Banita   +10 more
core   +1 more source

The functions of phospholipases and their hydrolysis products in plant growth, development and stress responses.

Progress in lipid research, 2022
Cell membranes are the initial site of stimulus perception from environment and phospholipids are the basic and important components of cell membranes. Phospholipases hydrolyze membrane lipids to generate various cellular mediators.
Usman Ali, Shaoping Lu, Tarig Fadlalla, Sidra Iqbal, H. Yue, Bao Yang, Yueyun Hong, Xuemin Wang, Liang Guo   +8 more
semanticscholar   +1 more source

Updating Phospholipase A2 Biology [PDF]

Biomolecules, 2020
The phospholipase A2 (PLA2) superfamily contains more than 50 enzymes in mammals that are subdivided into several distinct families on a structural and biochemical basis. In principle, PLA2 has the capacity to hydrolyze the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids, yet several enzymes in this superfamily ...
Makoto Murakami, Hiroyasu Sato, Yoshitaka Taketomi   +2 more
openaire   +3 more sources

Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]

, 2002
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes, Bertsch, Thomas, Fassbender, Klaus, Quintel, Michael, Samman, Michael, Zimmer, Wilma   +5 more
core   +1 more source

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

Toxins, 2021
A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments.
José María Gutiérrez, Laura-Oana Albulescu, Rachel H. Clare, Nicholas R. Casewell, Tarek Mohamed Abd El-Aziz, Teresa Escalante, Alexandra Rucavado   +6 more
doaj   +1 more source

Phospholipases C and D and Their Role in Biotic and Abiotic Stresses

Plants, 2021
Plants, as sessile organisms, have adapted a fine sensing system to monitor environmental changes, therefore allowing the regulation of their responses. As the interaction between plants and environmental changes begins at the surface, these changes are ...
Víctor M González-Mendoza, M. E. Sánchez-Sandoval, L. Castro-Concha, S. Hernández-Sotomayor   +3 more
semanticscholar   +1 more source