Results 61 to 70 of about 41,701 (205)

Synaptic lipid signaling

open access: yesJournal of Lipid Research, 2003
Neuronal cellular and intracellular membranes are rich in specialized phospholipids that are reservoirs of lipid messengers released by specific phospholipases and stimulated by neurotransmitters, neurotrophic factors, cytokines, membrane depolarization,
Nicolas G. Bazan
doaj   +1 more source

Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils [PDF]

open access: yes, 2017
Secreted phospholipases A2 (sPLA2s) are extracellular enzymes that catalyze the release of free fatty acids and lysophospholipids from membrane phospholipids and also bind to different receptors (e.g., PLA2R1 or integrins).
Borriello, Francesco   +11 more
core   +3 more sources

Differentiation of phospholipases A in mitochondria and lysosomes of rat liver

open access: yesJournal of Lipid Research, 1969
Highly purified mitochondria from rat liver contain a phospholipase A that catalyzes removal of 2-fatty acids, with a pH optimum above pH 8.0. Lysosomal preparations appeared to have two phospholipases A associated with them, one with a pH optimum at ...
Moseley Waite   +3 more
doaj   +1 more source

Calcium-independent phospholipases A2 and their roles in biological processes and diseases

open access: yesJournal of Lipid Research, 2015
Among the family of phospholipases A2 (PLA2s) are the Ca2+-independent PLA2s (iPLA2s) and they are designated group VI iPLA2s. In relation to secretory and cytosolic PLA2s, the iPLA2s are more recently described and details of their expression and roles ...
Sasanka Ramanadham   +5 more
doaj   +1 more source

Signalling Pinpointed to the Tip: The Complex Regulatory Network That Allows Pollen Tube Growth

open access: yesPlants, 2020
Plants display a complex life cycle, alternating between haploid and diploid generations. During fertilisation, the haploid sperm cells are delivered to the female gametophyte by pollen tubes, specialised structures elongating by tip growth, which is ...
Patricia Scholz   +3 more
doaj   +1 more source

Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom [PDF]

open access: yes, 2010
The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is
BARBOSA, AM   +6 more
core   +2 more sources

Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]

open access: yesPeerJ, 2014
Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma   +3 more
doaj   +2 more sources

Proteome and Peptidome of Vipera berus berus Venom

open access: yesMolecules, 2016
Snake venom is a rich source of peptides and proteins with a wide range of actions. Many of the venom components are currently being tested for their usefulness in the treatment of many diseases ranging from neurological and cardiovascular to cancer.
Aleksandra Bocian   +7 more
doaj   +1 more source

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

open access: yesToxins, 2020
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
Luciana A. Freitas-de-Sousa   +14 more
doaj   +1 more source

Black-necked spitting cobra (Naja nigricollis) phospholipases A2 may cause Trypanosoma brucei death by blocking endocytosis through the flagellar pocket

open access: yesScientific Reports, 2022
African trypanosomes, such as Trypanosoma brucei, are flagellated protozoa which proliferate in mammals and cause a variety of diseases in people and animals. In a mammalian host, the external face of the African trypanosome plasma membrane is covered by
Andrea Martos-Esteban   +6 more
doaj   +1 more source

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