Results 61 to 70 of about 96,105,277 (199)

Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]

open access: yesPeerJ, 2014
Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma   +3 more
doaj   +2 more sources

Hypotensive Snake Venom Components—A Mini-Review

open access: yesMolecules, 2019
Hypertension is considered a major public health issue due to its high prevalence and subsequent risk of cardiovascular and kidney diseases. Thus, the search for new antihypertensive compounds remains of great interest.
Orsolya Péterfi   +4 more
doaj   +1 more source

Myocardial phospholipases A2 and oxidative stress [PDF]

open access: yes, 2012
Heart and vascular diseases, in which oxidative stress plays an important role, are the most frequent cause of death in developed countries. Therefore today's researches focus on clarifying signaling pathway and their components that operates in these ...
Závišková, Kristýna
core  

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

open access: yesToxins, 2020
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
Luciana A. Freitas-de-Sousa   +14 more
doaj   +1 more source

Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells

open access: yesTranslational Oncology
Triple-negative breast cancer (TNBC) is the most lethal breast cancer subtype, leading to poor patient outcomes despite aggressive treatment with surgery, radiation, and chemotherapy. There are currently no clinical tests available which measure early on
Caitlin M. Tressler   +5 more
doaj   +1 more source

Avaliação da toxicidade de plantas ornamentais frente ao teste com artemia salina leach [PDF]

open access: yes, 2003
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Plantas tóxicas podem causar sérios danos a seres humanos e animais, com prejuízos significativos a saúde pública e a pecuária. Segundo o
MACHADO, Karina Zaia
core  

Intraspecific Variation of Centruroides Edwardsii Venom from Two Regions of Colombia

open access: yesToxins, 2014
We report the first description studies, partial characterization, and intraspecific difference of Centruroides edwardsii, Gervais 1843, venom. C. edwardsii from two Colombian regions (Antioquia and Tolima) were evaluated.
Sebastián Estrada-Gómez   +3 more
doaj   +1 more source

Mammalian Phospholipase A2: Phospholipase A2 Receptor

open access: yesBiological and Pharmaceutical Bulletin, 2004
The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family such as the mannose receptor. PLA2R regulates a variety of biological responses elicited by secretory phospholipase A2s (sPLA2s). Group IB sPLA2 acts as an endogenous ligand to induce cell proliferation and lipid mediator production ...
openaire   +3 more sources

Study of phospholipases in Trypanosoma brucei brucei

open access: yes, 2021
La trypanosomiase africaine est une parasitose vectorielle qui touche bon nombre de mammifères en Afrique. Parmi eux, nous pouvons compter les Hommes et les bêtes d’élevage. L’un des symptômes de cette pathologie chez l’animal est l’anémie. On ne connaît
Monic, Sarah
core  

The role of phospholipases in lipid modification and atherosclerosis

open access: yes, 2005
Phospholipases have received wide attention as it has become clear that several isoforms of the phospholipase family play a role in onset and progression of atherosclerosis.
Hofker, M.H.   +5 more
core   +1 more source

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