Results 211 to 220 of about 271,068 (255)
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Extracellular Phospholipase A2
1992Various lipids have been implicated in signal transduction and as precursors of lipid mediators, among them arachidonic acid (Dennis et al., 1991). Production of the prostaglandins, thromboxanes, and prostacyclins via the cyclooxygenase pathway, as well as the production of the leukotrienes and lipoxins via the lipoxygenase pathway, all depend on the ...
E A, Dennis, R A, Deems, L, Yu
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2015
Phospholipase A2s (PLA2s) are a group of enzymes that hydrolyze the sn-2 position of phospholipids to generate fatty acids and lysophospholipids, which serve as lipid mediators or their precursors. Mammalian genomes encode genes for more than 30 PLA2s or related enzymes, which are subdivided into several groups on the basis of their structures ...
Makoto Murakami, Yoshitaka Taketomi
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Phospholipase A2s (PLA2s) are a group of enzymes that hydrolyze the sn-2 position of phospholipids to generate fatty acids and lysophospholipids, which serve as lipid mediators or their precursors. Mammalian genomes encode genes for more than 30 PLA2s or related enzymes, which are subdivided into several groups on the basis of their structures ...
Makoto Murakami, Yoshitaka Taketomi
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Prostaglandins, Leukotrienes and Essential Fatty Acids, 2003
Considerable progress has been made in characterizing the individual participant enzymes and their relative contributions in the generation of eicosanoids, lipid mediators derived from arachidonic acid, such as prostaglandins and leukotrienes. However, the role of individual phospholipase (PL) A(2) enzymes in providing arachidonic acid to the ...
Bruno L, Diaz, Jonathan P, Arm
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Considerable progress has been made in characterizing the individual participant enzymes and their relative contributions in the generation of eicosanoids, lipid mediators derived from arachidonic acid, such as prostaglandins and leukotrienes. However, the role of individual phospholipase (PL) A(2) enzymes in providing arachidonic acid to the ...
Bruno L, Diaz, Jonathan P, Arm
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Phospholipase A2 receptor: a regulator of biological functions of secretory phospholipase A2
Prostaglandins & Other Lipid Mediators, 2002The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family that includes the mannose receptor. PLA2R regulates a variety of biological responses elicited by specific types of secretory PLA2s (sPLA2s).
Kohji, Hanasaki, Hitoshi, Arita
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Inhibition of phospholipase A2 and phospholipase C by polyamines
Archives of Biochemistry and Biophysics, 1978Abstract The polyamines spermine, spermidine, and putrescine inhibit the activity of phospholipase A2 (Naja naja) and phospholipase C (Clostridium welchii) on phospholipid vesicles and mitochondrial membranes as sources of substrate phospholipids. The inhibitory effect is highest for spermine and lowest for putrescine.
A M, Sechi +4 more
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Stimulation of Phospholipases A2 by Transglutaminases
1990Among the enzymes catalyzing post-translational modifications of proteins, transglutaminases (TG; EC 2.3.2.13) have been extensively characterized from the enzymological point of view (1–4). Nevertheless, the physiological role(s) of these enzymes, particularly the intracellular TGs, are still poorly understood.
E, Cordella-Miele +3 more
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1997
Part 1 Structure, distribution and function of phospholipase A2: history, classification, structure and function of phospholipase A2 expression of group II phospholipase A2 in human tissues determinants of the antimicrobial action of 14-kD phospholipase A2 downregulation of cytokine-induced synthesis and secretion of group II phospholipase A2 control ...
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Part 1 Structure, distribution and function of phospholipase A2: history, classification, structure and function of phospholipase A2 expression of group II phospholipase A2 in human tissues determinants of the antimicrobial action of 14-kD phospholipase A2 downregulation of cytokine-induced synthesis and secretion of group II phospholipase A2 control ...
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Journal of Lipid Mediators and Cell Signalling, 1995
M, Murakami, I, Kudo, K, Inoue
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M, Murakami, I, Kudo, K, Inoue
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Phospholipases C and D and Their Role in Biotic and Abiotic Stresses
Plants, 2021S M Teresa Hernández-Sotomayor +2 more
exaly