Results 21 to 30 of about 389,675 (351)
Cell, 1995 Ten years ago, describing what is new in phospholipid signaling in ten pages of Cell would have been easy; it would have been essentially a summary of the phospho-inositidase C (PIC) story: phosphatidylinositol(4,5)bisphos-phate (Ptdlns(4,5)P2) hydrolysis to inositiol(1,4,5)trisphos-phate (Ins(1",4,5)P3), with the synergistic action of Ca 2÷(mobilized ...
Divecha, Nullin, Irvine, Robin F.
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eLife, 2015 Polyunsaturated fatty acids (PUFAs) in phospholipids affect the physical properties of membranes, but it is unclear which biological processes are influenced by their regulation. For example, the functions of membrane arachidonate that are independent of
Tomomi Hashidate-Yoshida +14 more
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eLife, 2015 The role of specific phospholipids (PLs) in lipid transport has been difficult to assess due to an inability to selectively manipulate membrane composition in vivo.
Xin Rong +8 more
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Identification of a lipid scrambling domain in ANO6/TMEM16F
eLife, 2015 Phospholipid scrambling (PLS) is a ubiquitous cellular mechanism involving the regulated bidirectional transport of phospholipids down their concentration gradient between membrane leaflets.
Kuai Yu +5 more
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The inositol phospholipids [PDF]
Journal of Lipid Research, 1960 T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
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Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
eLife, 2014 Cationic antimicrobial peptides (CAPs) such as defensins are ubiquitously found innate immune molecules that often exhibit broad activity against microbial pathogens and mammalian tumor cells.
Ivan KH Poon +13 more
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Journal of Biomechanical Science and Engineering, 2013 In this study, the influence of phospholipid and protein constituents on friction and wear behavior of artificial hydrogel cartilage was investigated. A sliding pair of an ellipsoidal specimen of poly (vinyl alcohol) (PVA) hydrogel and a flat specimen of
Seido YARIMITSU +3 more
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Frontiers in Microbiology, 2021 The brucellae are facultative intracellular bacteria with a cell envelope rich in phosphatidylcholine (PC). PC is abundant in eukaryotes but rare in prokaryotes, and it has been proposed that Brucella uses PC to mimic eukaryotic-like features and avoid ...
Beatriz Aragón-Aranda +13 more
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Effect of dipolar-angle on phospholipid assembly [PDF]
Phys. Rev. E 95, 062703 (2017), 2016 We report the effect of lipid head-group dipole orientation on phase behaviour of phospholipid assembly. The work explains molecular-scale mechanism of ion-lipid, anesthetic-lipid interactions where reorientation of dipoles play important role in membrane potential modification. Molecular Dynamics simulations are performed to analyse structure-property
arxiv +1 more source
Opsin Is a Phospholipid Flippase [PDF]
Current Biology, 2011 Polar lipids must flip-flop rapidly across biological membranes to sustain cellular life [1, 2], but flipping is energetically costly [3] and its intrinsic rate is low. To overcome this problem, cells have membrane proteins that function as lipid transporters (flippases) to accelerate flipping to a physiologically relevant rate.
Sakmar, TP +9 more
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