Results 21 to 30 of about 565,738 (381)

Phospholipid signaling

Cell, 1995
Ten years ago, describing what is new in phospholipid signaling in ten pages of Cell would have been easy; it would have been essentially a summary of the phospho-inositidase C (PIC) story: phosphatidylinositol(4,5)bisphos-phate (Ptdlns(4,5)P2) hydrolysis to inositiol(1,4,5)trisphos-phate (Ins(1",4,5)P3), with the synergistic action of Ca 2÷(mobilized ...
Divecha, Nullin, Irvine, Robin F.
openaire   +3 more sources

Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site

mBio, 2020
Staphylococcus aureus utilizes the fatty acid (FA) kinase system to activate exogenous FAs for membrane synthesis. We developed a lipidomics workflow to determine the membrane phosphatidylglycerol (PG) molecular species synthesized by S.
Matthew W. Frank, Jiangwei Yao, Justin L. Batte, Jessica M. Gullett, Chitra Subramanian, Jason W. Rosch, Charles O. Rock   +6 more
doaj   +1 more source

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport

eLife, 2015
Polyunsaturated fatty acids (PUFAs) in phospholipids affect the physical properties of membranes, but it is unclear which biological processes are influenced by their regulation. For example, the functions of membrane arachidonate that are independent of
Tomomi Hashidate-Yoshida, Takeshi Harayama, Daisuke Hishikawa, Ryo Morimoto, Fumie Hamano, Suzumi M Tokuoka, Miki Eto, Miwa Tamura-Nakano, Rieko Yanobu-Takanashi, Yoshiko Mukumoto, Hiroshi Kiyonari, Tadashi Okamura, Yoshihiro Kita, Hideo Shindou, Takao Shimizu   +14 more
doaj   +1 more source

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

eLife, 2015
The role of specific phospholipids (PLs) in lipid transport has been difficult to assess due to an inability to selectively manipulate membrane composition in vivo.
Xin Rong, Bo Wang, Merlow M Dunham, Per Niklas Hedde, Jinny S Wong, Enrico Gratton, Stephen G Young, David A Ford, Peter Tontonoz   +8 more
doaj   +1 more source

Domain Growth Kinetics in a Cell-sized Liposome [PDF]

, 2005
We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump.
Bagatolli L. A., Baumgart T., Brown D. A., Furukawa H., Hamada T., Imai M., Karatekin E., Komura S., Korlach J., Kusumi A., Laradji M., Lipowsky R., McConnell H. M., Momura S. M., Noireaux V., Ohki K., Roux A., Saffman P. G., Seul M., Silvius J. R., Simons K., Taniguchi T., Veatch S. L., Veatch S. L., Veatch S. L., Veatch S. L., Yamashita Y., Yu W.   +27 more
core   +3 more sources

The inositol phospholipids [PDF]

Journal of Lipid Research, 1960
T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
openaire   +3 more sources

Identification of a lipid scrambling domain in ANO6/TMEM16F

eLife, 2015
Phospholipid scrambling (PLS) is a ubiquitous cellular mechanism involving the regulated bidirectional transport of phospholipids down their concentration gradient between membrane leaflets.
Kuai Yu, Jarred M Whitlock, Kyleen Lee, Eric A Ortlund, Yuan Yuan Cui, H Criss Hartzell   +5 more
doaj   +1 more source

The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

eLife, 2015
Maintenance of energy homeostasis depends on the highly regulated storage and release of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common metabolic disorders.
David Barneda, Joan Planas-Iglesias, Maria L Gaspar, Dariush Mohammadyani, Sunil Prasannan, Dirk Dormann, Gil-Soo Han, Stephen A Jesch, George M Carman, Valerian Kagan, Malcolm G Parker, Nicholas T Ktistakis, Judith Klein-Seetharaman, Ann M Dixon, Susan A Henry, Mark Christian   +15 more
doaj   +1 more source

Influence of Phospholipid and Protein Constituents on Tribological Properties of Artificial Hydrogel Cartilage Material

Journal of Biomechanical Science and Engineering, 2013
In this study, the influence of phospholipid and protein constituents on friction and wear behavior of artificial hydrogel cartilage was investigated. A sliding pair of an ellipsoidal specimen of poly (vinyl alcohol) (PVA) hydrogel and a flat specimen of
Seido YARIMITSU, Kazuhiro NAKASHIMA, Yoshinori SAWAE, Teruo MURAKAMI   +3 more
doaj   +1 more source

Permeation characteristics of tetracyclines in parallel artificial membrane permeation assay II: Effect of divalent metal ions and mucin

ADMET and DMPK, 2020
The bioavailability of tetracyclines is markedly decreased when co-administered with antacids, milk, or food containing Ca2+. Previously, it was suggested that the effective intestinal permeation of tetracycline (TC) was decreased due to Ca2+ linked ...
Sachika Yamauchi, Daisuke Inoue, Kiyohiko Sugano   +2 more
doaj   +1 more source