Results 41 to 50 of about 311,614 (314)

Application of the Box–Behnken Design in the Development of Amorphous PVP K30–Phosphatidylcholine Dispersions for the Co-Delivery of Curcumin and Hesperetin Prepared by Hot-Melt Extrusion

Pharmaceutics
Background: Curcumin and hesperetin are plant polyphenols known for their poor solubility. To address this limitation, we prepared amorphous PVP K30–phosphatidylcholine dispersions via hot-melt extrusion. Methods: This study aimed to evaluate the effects
Kamil Wdowiak, Lidia Tajber, Andrzej Miklaszewski, Judyta Cielecka-Piontek   +3 more
doaj   +1 more source

A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding

Journal of Lipid Research, 2023
Almost all the cholesterol in cellular membranes is associated with phospholipids in simple stoichiometric complexes. This limits the binding of sterol ligands such as filipin and perfringolysin O (PFO) to a small fraction of the total. We offer a simple
Yvonne Lange, S.M. Ali Tabei, Theodore L. Steck   +2 more
doaj   +1 more source

Phospholipid Scramblases [PDF]

Lipid Insights, 2015
The distribution of phospholipid types between the two leaflets of a membrane bilayer is a controlled feature of membrane structure. One of the two membrane catalytic activities governing this distribution randomizes the composition of the two leaflets–-the phospholipid scramblases.
openaire   +2 more sources

Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces [PDF]

, 1992
We present the application of reflection interference contrast microscopy (RICM) (1) to map the optical density of supported bilayers and vesicles and (2) to image the contact profile of phospholipid vesicles at surfaces.
Sackmann, E., Joachim Rädler, Rädler, Joachim O., Erich Sackmann   +3 more
core   +1 more source

Characterization of Milk Fat Globule Membrane Phospholipids in Colostrum of Holstein cows, Yaks and Buffaloes as Well as in Yak Colostrum and Mature Milk

Foods
Milk fat globule membrane (MFGM) phospholipids could promote the development of infants’ brain, nervous system and digestive system. This research conducted a comparative analysis of phospholipid composition in MFGM of colostrum from different bovine ...
Jie Luo, Yu Cao, Hui Zhou, Fangfang Yan, Shan Wu, Hao Zhang, Xiankang Fan   +6 more
doaj   +1 more source

Lipids of Prokaryotic Origin at the Base of Marine Food Webs

Marine Drugs, 2012
In particular niches of the marine environment, such as abyssal trenches, icy waters and hot vents, the base of the food web is composed of bacteria and archaea that have developed strategies to survive and thrive under the most extreme conditions.
Maria José Caramujo, Carla C. C. R. de Carvalho   +1 more
doaj   +1 more source

Comparative Study of Lipid and Fatty Acid Profile in Liver Tissues of Male and Female Silurus triostegus During the Catching Seasons

Aquatic Sciences and Engineering, 2021
In this study, seasonal variations of total fatty acid (FA), phospholipid (PL) and triacylglycerol (TAG) compositions in liver tissues of catfish (Silurus triostegus) were investigated. Samples of S. triostegus were obtained from Atatürk Dam Lake, Turkey,
Semra Kaçar, Mehmet Başhan
doaj   +1 more source

Opsin Is a Phospholipid Flippase [PDF]

Current Biology, 2011
Polar lipids must flip-flop rapidly across biological membranes to sustain cellular life [1, 2], but flipping is energetically costly [3] and its intrinsic rate is low. To overcome this problem, cells have membrane proteins that function as lipid transporters (flippases) to accelerate flipping to a physiologically relevant rate.
Sakmar, TP, Menon, I, Huber, T, Sanyal, S, Banerjee, S, Barré, P, Canis, S, Warren, JD, Hwa, J, Menon, AK   +9 more
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer’s Disease

Frontiers in Physiology, 2013
Not all of the mysteries of life lie in our genetic code. Some can be found buried in our membranes. These shells of fat, sculpted in the central nervous system into the cellular (and subcellular) boundaries of neurons and glia, are themselves complex ...
Steffany A L Bennett, Steffany A L Bennett, Nicolas eValenzuela, Nicolas eValenzuela, Hongbin eXu, Hongbin eXu, Bettina eFranko, Bettina eFranko, Stephen eFai, Stephen eFai, Daniel eFigeys, Daniel eFigeys   +11 more
doaj   +1 more source