μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]
, 2006 μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Fernández-Montalván, Amaury +5 more
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Frontiers in Microbiology, 2019 Lipopolysaccharides (LPS) in the outer membrane of Gram-negative bacteria provide the first line of defense against antibiotics and other harmful compounds. LPS biosynthesis critically depends on LpxC catalyzing the first committed enzyme in this process.
Nikolas Thomanek +7 more
doaj +1 more source
Effects of Gabaergic phenols on phospholipid bilayers as evaluated by 1H-NMR [PDF]
, 2013 The phenols propofol and thymol, and lately carvacrol, eugenol and chlorothymol, have been shown to act as positive allosteric modulators on GABAA receptor, which is the main inhibitory receptor of the central nervous system.
Fraceto, Leonardo Fernandes +4 more
core +1 more source
Metals, 2016 Biomaterial surface functionalization remains of great interest in the promotion of cell osteogenic induction. Previous studies highlighted the positive effects of porous Ti-6Al-4V and phospholipid coating on osteoblast differentiation and bone ...
Axel Deing +3 more
doaj +1 more source
Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]
, 2019 Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron +2 more
core +6 more sources
TECHNICAL AND CHEMICAL CHARACTERISTICS OF A DEEP-WATER SPECIES ANTIMORA MICROLEPIS
Известия ТИНРО, 2019 Antimora microlepis is considered as a new object of deep-water fishery. Its body length in the catches of 2018 was 40–80 cm, on average 56 cm, weight — 570–5670 g, on average 2170 g.
T. A. Davletshina +3 more
doaj +1 more source
The prolate-to-oblate shape transition of phospholipid vesicles in response to frequency variation of an AC electric field can be explained by the dielectric anisotropy of a phospholipid bilayer [PDF]
, 2007 The external electric field deforms flaccid phospholipid vesicles into spheroidal bodies, with the rotational axis aligned with its direction. Deformation is frequency dependent: in the low frequency range (~ 1 kHz), the deformation is typically prolate,
Ambjörnsson T +19 more
core +1 more source
Biomimetic lipid–fluorescein probe for cellular bioimaging
Frontiers in Chemistry, 2023 Fluorescence probe is one of the most powerful tools for cellular imaging. Here, three phospholipid-mimicking fluorescent probes (FP1–FP3) comprising fluorescein and two lipophilic groups of saturated and/or unsaturated C18 fatty acids were synthesized ...
Hyungkyu Moon +5 more
doaj +1 more source
Journal of Lipid Research, 2023 Almost all the cholesterol in cellular membranes is associated with phospholipids in simple stoichiometric complexes. This limits the binding of sterol ligands such as filipin and perfringolysin O (PFO) to a small fraction of the total. We offer a simple
Yvonne Lange +2 more
doaj +1 more source
Liposomal-polyene preliposomal powder and method for its preparation [PDF]
, 1993 A method is disclosed for preparing a stable preliposomal powder which, when reconstituted with water or saline solution, forms a suspension of liposomes containing a polyene drug, such as nystatin. The method involves the steps of combining at least one
Lenk, Robert P. +2 more
core +1 more source