Results 21 to 30 of about 169 (165)
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell +7 more
wiley +1 more source
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett +19 more
wiley +1 more source
Phospholipids in Mediterranean Cephalopods
Abstract Polar lipids of the cephalopods Eledone moschata, Sepia officinalis and Todarodes sagittatus mantle, represent 50.5%, 66.1% and 74.2% of wet tissue respectively. On the other hand the polar lipids of these three species of cephalopods constitute of 80.8%, 94.8% and 93.7% of phospholipids, respectively.
Sinanoglou, V.J. +1 more
openaire +3 more sources
Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
Putting the 'P' into Phospholipids
Despite almost hundred years of dedicated research, the synthesis of phospholipids remains a challenge. Here, we briefly review important trends and point out possible future directions that might lead to interesting new probes for the membrane environment. An improved liposome purification and concentration protocol rounds up the article.
Fedotenko Illya A. +4 more
openaire +4 more sources
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni +13 more
wiley +1 more source
Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores +12 more
wiley +1 more source
Studies on phospholipids of meat
牛の筋肉の部位別および肥育をとくに行なわない牛と肥育牛によつて,総燐脂質の脂肪酸組成がどのようにかわるかを明らかにするためと,同一筋肉中に存在する燐脂質以外の脂質の脂肪酸組成との比較を目的として,肥育をとくに行なわない牛と肥育牛の咬筋,背最長筋および大腿二頭筋の燐脂質,コレステリンエステルおよびトリグリセリドの脂肪酸組成および遊離の脂肪酸の分布をガスクロマトグラフィーにより分析したところ,次のような知見が得られた.1. コレステリンエステル,トリグリセリドの脂肪酸組成および遊離の脂肪酸の分布には筋肉別に差がみられないが,肥育をとくに行なわない牛と肥育牛を比較した場合,肥育牛にはステアリン酸が少なく,オレイン酸が多かつた.2.
Takeo NAKANISHI, Kyozo SUYAMA
openaire +11 more sources

