Results 51 to 60 of about 209,802 (322)

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

open access: yesAdvanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker   +7 more
wiley   +1 more source

Collective dynamics in phospholipid bilayers investigated by inelastic neutron scattering: Exploring the dynamics of biological membranes with neutrons [PDF]

open access: yesPhysica B 350 (2004)136 --139, 2004
We present the first inelastic neutron scattering study of the short wavelength dynamics in a phospholipid bilayer. We show that inelastic neutron scattering using a triple-axis spectrometer at the high flux reactor of the ILL yields the necessary resolution and signal to determine the dynamics of model membranes.
arxiv   +1 more source

Kinetic dependence of phospholipase A2 activity on the detergent Triton X-100

open access: yesJournal of Lipid Research, 1973
A kinetic analysis is presented for the dependence of one form of phospholipase A2 from cobra (Naja naja) venom on the presence of the nonionic detergent Triton X-100 for its activity towards egg phosphatidylcholine and synthetic dipalmitoyl ...
Edward A. Dennis
doaj  

Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery

open access: yesPharmaceutics, 2023
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles produced from cholesterol and phospholipids. Recently, liposomes have been widely administered intranasally for systemic and brain delivery. From the nasal cavity, liposome-
Van-An Duong   +2 more
doaj   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

open access: yesAdvanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André   +3 more
wiley   +1 more source

Isolation and characterization of a phospholipase A2 from an inflammatory exudate

open access: yesJournal of Lipid Research, 1978
Sterile peritoneal exudates produced in rabbits injected with 1% glycogen contain a phospholipase A activity in a cell-free supernatant fraction that hydrolyzed a synthetic phospholipid (1,2-diacyl-sn-glycero-3-phospho-ethanolamine) and phospholipids of ...
R Franson, Dr   +4 more
doaj  

Special Issue: Candida and Candidiasis

open access: yesJournal of Fungi, 2018
This special issue highlights emerging topics related to Candida, the most prevalent fungal pathogen in the hospital setting. The advantages and limitations of new, non-culture based diagnostic techniques are discussed.
Jeniel E. Nett
doaj   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Frequency-dependent electrodeformation of giant phospholipid vesicles in AC electric field [PDF]

open access: yesJ Biol Phys 36 (2010) 339-354, 2010
A model of vesicle electrodeformation is described which obtains a parametrized vesicle shape by minimizing the sum of the membrane bending energy and the energy due to the electric field. Both the vesicle membrane and the aqueous media inside and outside the vesicle are treated as leaky dielectrics, and the vesicle itself is modelled as a nearly ...
arxiv   +1 more source

Role of lipids in the structure and function of biological membranes

open access: yesJournal of Lipid Research, 1966
The concept of biological membranes as vesicular or tubular continua built up of nesting repeating units has been systematically explored and some of the relevant experimental work has been assembled.
David E. Green, Alexander Tzagoloff
doaj  

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